2-[4-(Chloroacetyl)piperazin-1-yl]pyrimidine

Base Information

Chemical Name:2-[4-(Chloroacetyl)piperazin-1-yl]pyrimidine
CAS No.:425634-97-5
Molecular Formula:C10H13ClN4O
Molecular Weight:240.692
Hs Code.:2933990090
European Community (EC) Number:855-099-0
ChEMBL ID:CHEMBL4210524
Mol file:425634-97-5.mol

Synonyms:2-[4-(chloroacetyl)piperazin-1-yl]pyrimidine;425634-97-5;2-chloro-1-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone;2-Chloro-1-(4-(pyrimidin-2-yl)piperazin-1-yl)ethanone;2-chloro-1-[4-(pyrimidin-2-yl)piperazin-1-yl]ethanone;2-chloro-1-[4-(pyrimidin-2-yl)piperazin-1-yl]ethan-1-one;2-Chloro-1-(4-(pyrimidin-2-yl)piperazin-1-yl)ethan-1-one;2-[4-(chloroacetyl)-1-piperazinyl]pyrimidine;SCHEMBL5887976;CHEMBL4210524;Piperazine, 1-(chloroacetyl)-4-(2-pyrimidinyl)- (9CI);QOSZOMQTJFDQSE-UHFFFAOYSA-N;MFCD00860990;STL581902;AKOS003801304;LS-04108;CS-0452445;EN300-31273;2-Chloro-1-[4-(2-pyrimidinyl)-1-piperazinyl]ethanone

Suppliers and Price of 2-[4-(Chloroacetyl)piperazin-1-yl]pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
2-[4-(Chloroacetyl)piperazin-1-yl]pyrimidine
500mg
$ 158.00

Biosynth Carbosynth
2-[4-(Chloroacetyl)piperazin-1-yl]pyrimidine
500 mg
$ 100.00

Biosynth Carbosynth
2-[4-(Chloroacetyl)piperazin-1-yl]pyrimidine
250 mg
$ 57.50

Biosynth Carbosynth
2-[4-(Chloroacetyl)piperazin-1-yl]pyrimidine
5 g
$ 578.00

Biosynth Carbosynth
2-[4-(Chloroacetyl)piperazin-1-yl]pyrimidine
2 g
$ 289.00

Biosynth Carbosynth
2-[4-(Chloroacetyl)piperazin-1-yl]pyrimidine
1 g
$ 170.00

American Custom Chemicals Corporation
2-[4-(CHLOROACETYL)PIPERAZIN-1-YL]PYRIMIDINE 95.00%
2.5G
$ 983.88

AK Scientific
2-[4-(Chloroacetyl)piperazin-1-yl]pyrimidine
500mg
$ 263.00

Total 3 raw suppliers

Chemical Property of 2-[4-(Chloroacetyl)piperazin-1-yl]pyrimidine

Chemical Property:

Boiling Point:454.9±55.0 °C(Predicted)
PKA:4.87±0.33(Predicted)
PSA：49.33000
Density:1.323±0.06 g/cm3(Predicted)
LogP:0.36690
XLogP3:0.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:240.0777887
Heavy Atom Count:16
Complexity:237

Purity/Quality:

97% ^*data from raw suppliers

2-[4-(Chloroacetyl)piperazin-1-yl]pyrimidine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1C2=NC=CC=N2)C(=O)CCl

Technology Process of 2-[4-(Chloroacetyl)piperazin-1-yl]pyrimidine

There total 2 articles about 2-[4-(Chloroacetyl)piperazin-1-yl]pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 20980-22-7
N-(2-pyridinyl)piperazine

: 79-04-9
chloroacetyl chloride

: 425634-97-5
2-chloro-1-[4-(pyrimidin-2-yl) piperazin-1-yl]ethanone

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; at 20 ℃; for 2.5h; Reflux;
DOI:10.1111/cbdd.12041 DOI:10.1111/cbdd.12041