Dodecanoic acid, 12-[[(phenylmethoxy)carbonyl]amino]-

Base Information

• Chemical Name: Dodecanoic acid, 12-[[(phenylmethoxy)carbonyl]amino]-
• CAS No.: 4272-07-5
• Molecular Formula: C20H31NO4
• Molecular Weight: 349.47
• Hs Code.: 2924299090
• Mol file: 4272-07-5.mol

Synonyms:12-N-(benzyloxycarbonyl)aminododecanoic acid;12-(Benzyloxycarbonyl)-amino-dodecanoic acid;12-(Benzyloxycarbonylamino)dodecanoic acid;12-benzyloxycarbonylaminododecanoic acid;N-Benzyloxycarbonyl-12-amino-dodecansaeure;

Chemical Property of Dodecanoic acid, 12-[[(phenylmethoxy)carbonyl]amino]-

Chemical Property:

• PSA: 75.63000
• LogP: 5.28930

Purity/Quality:

98% ^*data from raw suppliers

12-(Cbz-amino)dodecanoicacid 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Dodecanoic acid, 12-[[(phenylmethoxy)carbonyl]amino]-

There total 6 articles about Dodecanoic acid, 12-[[(phenylmethoxy)carbonyl]amino]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

methyl 12-(benzyloxycarbonylamino)dodecanoate (1129295-44-8) → 12-(((benzyloxy)carbonyl)amino)dodecanoic acid (4272-07-5)

Guidance literature:

With lithium hydroxide; In tetrahydrofuran; water; at 20 ℃; for 10h;

DOI:10.1002/ejoc.201200726

Reference yield: 85.0%

benzyl chloroformate (501-53-1,94274-21-2) + 12-Aminododecanoic acid (693-57-2) → 12-(((benzyloxy)carbonyl)amino)dodecanoic acid (4272-07-5)

Guidance literature:

In sodium hydroxide; diethyl ether; at 20 ℃;

DOI:10.1016/j.tet.2007.02.065

Reference yield: 50.0%

→ 12-(((benzyloxy)carbonyl)amino)dodecanoic acid (4272-07-5)

Guidance literature:

upstream raw materials:

12-aminolauric acid hydrogen chloride salt

benzyl chloroformate

12-Aminododecanoic acid

methyl 12-(benzyloxycarbonylamino)dodecanoate

Downstream raw materials:

(+)-1-O-[12-N-(benzyloxycarbonyl)aminododecanoyl]-3-O-(4-methoxybenzyl)-sn-glycerol

methyl 2-[(12-benzyloxycarbonylamino)dodecanoyl]amino-2-deoxy-4,6-isopropylidene-3-O-tetradecanoyl-α-D-glucopyranoside

tetrabenzyl 4,5-{1-O-[12-N-(benzyloxycarbonyl)aminododecanoyl]-2,3,6-tri-O-methoxymethyl-myo-inosityl}bisphosphate

C₁₈H₃₇NO₁₃P₂