3-(1-Benzofuran-2-yl)propanoic acid

Base Information

Chemical Name:3-(1-Benzofuran-2-yl)propanoic acid
CAS No.:21683-86-3
Molecular Formula:C11H10 O3
Molecular Weight:190.2
Hs Code.:
European Community (EC) Number:849-437-6
ChEMBL ID:CHEMBL4218907
Mol file:21683-86-3.mol

Synonyms:3-(1-benzofuran-2-yl)propanoic acid;21683-86-3;3-(Benzofuran-2-yl)propanoic acid;SCHEMBL7248298;CHEMBL4218907;3-(Benzofuran-2-yl)propanoicacid;WAA68386;MFCD07690609;AKOS000119196;AS-62325;3-(1-BENZOFURAN-2-YL)PROPANOICACID;EN300-15389;W15989;A911404;J-803025;F8880-0178;Z137628830

Suppliers and Price of 3-(1-Benzofuran-2-yl)propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-(1-benzofuran-2-yl)propanoicAcid
10mg
$ 45.00

Crysdot
3-(Benzofuran-2-yl)propanoicacid 97%
1g
$ 564.00

American Custom Chemicals Corporation
3-(1-BENZOFURAN-2-YL)PROPANOIC ACID 95.00%
5G
$ 1928.08

American Custom Chemicals Corporation
3-(1-BENZOFURAN-2-YL)PROPANOIC ACID 95.00%
2.5G
$ 1473.14

American Custom Chemicals Corporation
3-(1-BENZOFURAN-2-YL)PROPANOIC ACID 95.00%
1G
$ 983.52

AK Scientific
3-(1-Benzofuran-2-yl)propanoicacid
500mg
$ 546.00

AK Scientific
3-(1-Benzofuran-2-yl)propanoicacid
100mg
$ 268.00

Total 8 raw suppliers

Chemical Property of 3-(1-Benzofuran-2-yl)propanoic acid

Chemical Property:

Vapor Pressure:3.16E-05mmHg at 25°C
Melting Point:145-146 °C(Solv: benzene (71-43-2))
Boiling Point:341.2°Cat760mmHg
PKA:4.51±0.10(Predicted)
Flash Point:160.1°C
PSA：50.44000
Density:g/cm³
LogP:2.45000
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:190.062994177
Heavy Atom Count:14
Complexity:215

Purity/Quality:

97% ^*data from raw suppliers

3-(1-benzofuran-2-yl)propanoicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C=C(O2)CCC(=O)O

Technology Process of 3-(1-Benzofuran-2-yl)propanoic acid

There total 10 articles about 3-(1-Benzofuran-2-yl)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 546084-15-5
methyl 3-(benzofuran-2-yl)propanoate

: 21683-86-3
3-(Benzofuran-2-yl)propionic acid

Guidance literature:: With sodium hydroxide; In 1,4-dioxane; at 20 ℃; for 1h;
DOI:10.1002/ejoc.201600194

Reference yield: 52.0%

: 7522-79-4
2-vinylbenzofuran

: 124-38-9,18923-20-1
carbon dioxide

: 21683-86-3
3-(Benzofuran-2-yl)propionic acid

: C₁₂H₁₀O₅

Guidance literature:: With 1,2,2,6,6-pentamethylpiperidine; [1,1';4',1'']terphenyl; water; In hexane; N,N-dimethyl-formamide; at 35 - 38 ℃; for 0.133333h; under 760.051 Torr; Schlenk technique; UV-irradiation; Flow reactor;
DOI:10.1021/jacs.7b05942

Reference yield:

: 3199-61-9
ethyl coumarilate

: 21683-86-3
3-(Benzofuran-2-yl)propionic acid

Guidance literature:: Multi-step reaction with 5 steps

1: hydrazine hydrate / ethanol / 5 h / Heating

2: pyridine / 6 h / 0 °C

3: Na₂CO₃ / ethane-1,2-diol / 0.05 h / 160 °C

4: 1.3 g / piperidine / pyridine / 6 h / Heating

5: 2percent sodium amalgam

With piperidine; sodium amalgam; sodium carbonate; hydrazine hydrate; In pyridine; ethanol; ethylene glycol;