5-(Dimethylamino)napthalene-1-sulfonyl-l-aspartic acid

Base Information

• Chemical Name: 5-(Dimethylamino)napthalene-1-sulfonyl-l-aspartic acid
• CAS No.: 42808-07-1
• Molecular Formula: C16H18N2O6S
• Molecular Weight: 366.38900
• DSSTox Substance ID: DTXSID001313797
• Mol file: 42808-07-1.mol

Synonyms:42808-07-1;dansyl-dl-aspartic acid;Dansyl-DL-aspartic acid di(cyclohexylammonium) salt;5-(Dimethylamino)napthalene-1-sulfonyl-l-aspartic acid;SCHEMBL13884437;DTXSID001313797;2-[[5-(dimethylamino)naphthalen-1-yl]sulfonylamino]butanedioic acid;2-(5-(dimethylamino)naphthalene-1-sulfonamido)succinic acid;N-([5-(Dimethylamino)-1-naphthyl]sulfonyl)aspartic acid #

Chemical Property of 5-(Dimethylamino)napthalene-1-sulfonyl-l-aspartic acid

Chemical Property:

• PSA: 132.39000
• LogP: 2.58370
• Storage Temp.: −20°C
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 7
• Exact Mass: 366.08855747
• Heavy Atom Count: 25
• Complexity: 600

Purity/Quality:

Dansyl-DL-asparticAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)C1=CC=CC2=C1C=CC=C2S(=O)(=O)NC(CC(=O)O)C(=O)O
• Uses: Dansyl-DL-aspartic Acid is an amino acid, an amphoteric chiral model compound used in capillary electrophoresis and in enantioseparation of active pharmaceutical ingredients and other bio molecules.

Technology Process of 5-(Dimethylamino)napthalene-1-sulfonyl-l-aspartic acid

There total 2 articles about 5-(Dimethylamino)napthalene-1-sulfonyl-l-aspartic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-(dimethylamino)naphth-1-ylsulfonyl chloride (605-65-2) + aspartic Acid (617-45-8,25608-40-6,27881-03-4,32505-46-7,52526-39-3) → dansyl-D,L-aspartic acid (42808-07-1)

Guidance literature:

With sodium hydrogencarbonate; In water; acetonitrile; at 20 ℃;

DOI:10.1002/(SICI)1099-1344(199806)41:6<477::AID-JLCR104>3.0.CO;2-3

Reference yield:

→ dansyl-D,L-aspartic acid (42808-07-1)

Guidance literature:

DL-Asparaginsaeure, Dansylchlorid, Na2CO3;

Reference yield:

dansyl-D,L-aspartic acid (42808-07-1) → dansyl-L-aspartic acid (1100-24-9) + dansyl-D-aspartic acid

Guidance literature:

DOI:10.1021/ac950698c

upstream raw materials:

5-(dimethylamino)naphth-1-ylsulfonyl chloride

aspartic Acid

Downstream raw materials:

dansyl-L-aspartic acid