(1S,3S)-1,2,3,4,4a,9a-Hexahydro-4α-hydroxymethyl-9,10-dimethyl-1,4-(epoxymethano)-9aβ,4aβ-(iminoethano)-13-oxo-9H-carbazole 3-[(E)-α-ethylideneacetic acid]methyl ester

Base Information

• Chemical Name: (1S,3S)-1,2,3,4,4a,9a-Hexahydro-4α-hydroxymethyl-9,10-dimethyl-1,4-(epoxymethano)-9aβ,4aβ-(iminoethano)-13-oxo-9H-carbazole 3-[(E)-α-ethylideneacetic acid]methyl ester
• CAS No.: 20594-89-2
• Molecular Formula: C₂₃H₂₈N₂O₅
• Molecular Weight: 412.486
• Mol file: 20594-89-2.mol

Synonyms:Erinine,21,23-deepoxy-23-hydroxy-21-methoxy-; Eripine (8CI); 1H,9H-1,4-Ethano-9a,4a-(iminoethano)pyrano[3,4-b]indole-13-aceticacid, a-ethylidene-3,4-dihydro-4-(hydroxymethyl)-9,10-dimethyl-3-oxo-, methylester, [1R-[1a,4b,4ab,9ab,13(E)]]-

Chemical Property of (1S,3S)-1,2,3,4,4a,9a-Hexahydro-4α-hydroxymethyl-9,10-dimethyl-1,4-(epoxymethano)-9aβ,4aβ-(iminoethano)-13-oxo-9H-carbazole 3-[(E)-α-ethylideneacetic acid]methyl ester

Chemical Property:

• PSA: 79.31000
• LogP: 1.45220

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1S,3S)-1,2,3,4,4a,9a-Hexahydro-4α-hydroxymethyl-9,10-dimethyl-1,4-(epoxymethano)-9aβ,4aβ-(iminoethano)-13-oxo-9H-carbazole 3-[(E)-α-ethylideneacetic acid]methyl ester

There total 3 articles about (1S,3S)-1,2,3,4,4a,9a-Hexahydro-4α-hydroxymethyl-9,10-dimethyl-1,4-(epoxymethano)-9aβ,4aβ-(iminoethano)-13-oxo-9H-carbazole 3-[(E)-α-ethylideneacetic acid]methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

noreripinal (69734-93-6) → eripine (20594-89-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 75 mg / Et₃SiH, CF₃CO₂H / 4 h

2: 25 mg / CF₃CO₂H, Et₃SiH / H₂O / 6 h

With triethylsilane; trifluoroacetic acid; In water;

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + noreripine (84981-41-9) → eripine (20594-89-2)

Guidance literature:

With triethylsilane; trifluoroacetic acid; In water; for 6h;

Reference yield:

eripinal (69734-95-8) → eripine (20594-89-2)

Guidance literature:

With triethylsilane; trifluoroacetic acid; for 12h;

upstream raw materials:

formaldehyd

noreripine

eripinal

noreripinal

Downstream raw materials:

Isoerimin

erinine

Refernces