CIS-3-HYDROXY-DL-PROLINE

Base Information

Chemical Name:CIS-3-HYDROXY-DL-PROLINE
CAS No.:4298-05-9
Molecular Formula:C₅H₉NO₃
Molecular Weight:131.131
Hs Code.:2933990090
Mol file:4298-05-9.mol

Synonyms:tert-butyl cis-3-hydroxycyclobutanecarboxylate;cis-3-hydroxy-cyclobutanecarboxylic acid tert-butyl ester;cis-tert-Butyl 3-hydroxycyclobutanecarboxylate;

Suppliers and Price of CIS-3-HYDROXY-DL-PROLINE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
cis-3-Hydroxy-DL-proline
5mg
$ 460.00

TRC
cis-3-Hydroxy-DL-proline
5mg
$ 160.00

TRC
cis-3-Hydroxy-DL-proline
50mg
$ 1260.00

Sigma-Aldrich
cis-3-Hydroxy-DL-proline 95%
10mg
$ 365.00

Medical Isotopes, Inc.
cis-3-Hydroxy-DL-proline
50 mg
$ 2200.00

American Custom Chemicals Corporation
CIS-3-HYDROXY-DL-PROLINE 95.00%
250MG
$ 650.00

American Custom Chemicals Corporation
CIS-3-HYDROXY-DL-PROLINE 95.00%
5MG
$ 504.04

Total 13 raw suppliers

Chemical Property of CIS-3-HYDROXY-DL-PROLINE

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:232oC (dec.)(lit.)
Boiling Point:355.233oC at 760 mmHg
PKA:2.03±0.40(Predicted)
Flash Point:168.639oC
PSA：69.56000
Density:1.395g/cm3
LogP:-0.87740
Storage Temp.:Store at 0-5°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

cis-3-Hydroxy-DL-proline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 22-24/25

MSDS Files:: Total 1 MSDS from other Authors

Useful:

Uses cis-3-Hydroxy-DL-proline is a derivative of DL-Proline (P756050), a racemic mixture of both L-Proline (P755995) and D-Proline (P755990).

Technology Process of CIS-3-HYDROXY-DL-PROLINE

There total 31 articles about CIS-3-HYDROXY-DL-PROLINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 147-85-3,25191-13-3,37159-97-0,4305-67-3,4607-28-7
L-proline

: 567-35-1,567-36-2,4298-05-9,4298-06-0,4298-08-2,14916-76-8,62182-84-7,104069-26-3,118492-86-7,119677-21-3
(2S,3R)-3-hydroxyproline

Guidance literature:: With ferrous(II) sulfate heptahydrate; cis-3-proline hydroxylase type II; sodium L-ascorbate; at 37 ℃; for 16h; stereospecific reaction;
DOI:10.3762/bjoc.7.193

Reference yield: 98.0%

: 1262015-07-5
(2S,3R)-N-(benzyloxycarbonyl)-3-hydroxypyrrolidine-2-carboxylic acid

: 567-35-1,567-36-2,4298-05-9,4298-06-0,4298-08-2,14916-76-8,62182-84-7,104069-26-3,118492-86-7,119677-21-3
(2S,3R)-3-hydroxyproline

Guidance literature:: With hydrogen; palladium(II) hydroxide; In methanol; at 25 ℃; for 12h; under 4137.29 Torr;
DOI:10.1016/j.tetlet.2010.10.086

Reference yield: 90.0%

: 166383-67-1
(2S,3R)-1-(tert-butoxycarbonyl)-3-(tert-butyldimethylsiloxy)pyrrolidine-2-carboxylic acid

: 567-35-1,567-36-2,4298-05-9,4298-06-0,4298-08-2,14916-76-8,62182-84-7,104069-26-3,118492-86-7,119677-21-3
(2S,3R)-3-hydroxyproline

Guidance literature:: (2S,3R)-1-(tert-butoxycarbonyl)-3-(tert-butyldimethylsiloxy)pyrrolidine-2-carboxylic acid; With trifluoroacetic acid; In dichloromethane; at 0 - 20 ℃; for 2h;

With methyloxirane; In methanol; at 20 ℃; for 2h;