1H-Pyrrole-2-carboxaldehyde, 5-(4-methoxyphenyl)-

Base Information

Chemical Name:1H-Pyrrole-2-carboxaldehyde, 5-(4-methoxyphenyl)-
CAS No.:431039-10-0
Molecular Formula:C12H11NO2
Molecular Weight:
Hs Code.:
Mol file:431039-10-0.mol

Synonyms:

Suppliers and Price of 1H-Pyrrole-2-carboxaldehyde, 5-(4-methoxyphenyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 3 raw suppliers

Chemical Property of 1H-Pyrrole-2-carboxaldehyde, 5-(4-methoxyphenyl)-

Chemical Property:

Purity/Quality:: >98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1H-Pyrrole-2-carboxaldehyde, 5-(4-methoxyphenyl)-

There total 2 articles about 1H-Pyrrole-2-carboxaldehyde, 5-(4-methoxyphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 104-92-7
1-bromo-4-methoxy-benzene

: 431039-10-0
5-(4-methoxyphenyl)-1H-pyrrole-2-carbaldehyde

Guidance literature:: Multi-step reaction with 3 steps

1.1: palladium diacetate; XPhos; potassium phosphate / butan-1-ol / 2 h / 23 °C / Inert atmosphere

2.1: sodium methylate / tetrahydrofuran; methanol / 23 °C / Inert atmosphere

3.1: trichlorophosphate / dichloromethane / 0.08 h / Inert atmosphere

3.2: Inert atmosphere

3.3: 23 °C / Inert atmosphere

With potassium phosphate; sodium methylate; palladium diacetate; XPhos; trichlorophosphate; In tetrahydrofuran; methanol; dichloromethane; butan-1-ol; 1.1: |Suzuki Coupling / 3.1: |Vilsmeier-Haack Formylation / 3.2: |Vilsmeier-Haack Formylation / 3.3: |Vilsmeier-Haack Formylation;
DOI:10.1021/jacs.7b04448

Reference yield:

: 198981-85-0
2-(4-methoxyphenyl)-1H-pyrrole-1-carboxylic acid 1,1-dimethylethyl ester

: 431039-10-0
5-(4-methoxyphenyl)-1H-pyrrole-2-carbaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium methylate / tetrahydrofuran; methanol / 23 °C / Inert atmosphere

2.1: trichlorophosphate / dichloromethane / 0.08 h / Inert atmosphere

2.2: Inert atmosphere

2.3: 23 °C / Inert atmosphere

With sodium methylate; trichlorophosphate; In tetrahydrofuran; methanol; dichloromethane; 2.1: |Vilsmeier-Haack Formylation / 2.2: |Vilsmeier-Haack Formylation / 2.3: |Vilsmeier-Haack Formylation;
DOI:10.1021/jacs.7b04448