198981-85-0

Basic information

• Product Name: 1H-Pyrrole-1-carboxylic acid, 2-(4-methoxyphenyl)-, 1,1-dimethylethyl ester
• CAS NO: 198981-85-0
• Molecular Formula: C16H19NO3
• Molecular Weight: 273.332
• Mol File: 198981-85-0.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: 1H-Pyrrole-1-carboxylic acid, 2-(4-methoxyphenyl)-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrole-1-carboxylic acid, 2-(4-methoxyphenyl)-, 1,1-dimethylethyl ester(198981-85-0)
• EPA Substance Registry System: 1H-Pyrrole-1-carboxylic acid, 2-(4-methoxyphenyl)-, 1,1-dimethylethyl ester(198981-85-0)

Safety Data

• Hazardous Substances Data: 198981-85-0(Hazardous Substances Data)

Upstream product

• 5176-27-2 N-tert-butyloxycarbonyl-pyrrole 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 135884-31-0 N-boc-2-pyrroleboronic acid 
• 459-64-3 4-methoxybenzenediazonium tetrafluoroborate 
• 104-94-9 4-methoxy-aniline 
• 92136-39-5 N-tert-Butoxycarbonyl-1-amino-3-propyne 
• 100-07-2 4-methoxy-benzoyl chloride 
• 856702-61-9 tert-butyl 2-(methylthio)-1H-pyrrole-1-carboxylate 
• 696-62-8 para-iodoanisole 
• 172282-33-6 N-(tert-butoxycarbonyl)-2-(trimethylstannyl)pyrrole 
• 879904-82-2 2-(hydroxydimethylsilyl)-1H-pyrrole-1-carboxylic acid 1,1-dimethylethyl ester 
• 5720-07-0 4-methoxyphenylboronic acid 
• 117657-37-1 2-bromo-pyrrole-1-carboxylic acid tert-butyl ester 

Downstream Products

• 1159581-63-1 tert-butyl 4-iodo-2-(4-methoxy-phenyl)-1H-pyrrole-1-carboxylate 
• 1333469-94-5 2,5-bis(5-(4-methoxyphenyl)-1H-pyrrol-3-yl)pyrimidine 
• 431039-10-0 5-(4-methoxyphenyl)-1H-pyrrole-2-carbaldehyde 
• 1497397-05-3 C₂₅H₂₄BF₂N₃O₃ 
• 864948-51-6 trimethyl 1,1'-bis-(4-methoxyphenyl)-5-(3-hydroxy-4-aminophenyl-N,N,O-triacetate)dipyrromethane 
• 4995-12-4 2-(4-methoxyphenyl)-1H-pyrrole 

Relevant articles and documents

σ-Bond initiated generation of aryl radicals from aryl diazonium salts

σ-Bond nucleophiles and molecular oxygen transform aryl diazonium salts into aryl radicals. Experimental and computational studies show that Hantzsch esters transfer hydride to aryl diazonium species, and that oxygen initiates radical fragmentation of the diazene intermediate to produce aryl radicals. The operational simplicity of this addition-fragmentation process for the generation of aryl radicals, by a polar-radical crossover mechanism, has been illustrated in a variety of bond-forming reactions.

Electrolytic cross-Coupling of arenediazonium salts and heteroarenes

The cathodic reduction-induced cross-coupling of arenediazonium salts and heteroarenes was employed to prepare heterobiaryl derivatives. This reaction is attractive because it allows the direct arylation of an aromatic C-H bond in a heteroarene derivative. A radical chain mechanism appears to be involved.

Original design of fluorescent ligands by fusing BODIPY and melatonin neurohormone

An original design and synthesis of fluorescent ligands for melatonin receptor studies is presented and consists in the fusion of the endogenous ligand with the fluorescent BODIPY core. Probes I-IV show high affinities for MT1 and MT2 melatonin receptors and exhibit fluorescence properties compatible with cell observation.