Ethyl 2-(2-(methylthio)-6-oxo-1,6-dihydropyrimidin-5-yl)acetate

Base Information

Chemical Name:Ethyl 2-(2-(methylthio)-6-oxo-1,6-dihydropyrimidin-5-yl)acetate
CAS No.:29571-44-6
Molecular Formula:C9H12 N2 O3 S
Molecular Weight:228.2682
Hs Code.:2933599090
NSC Number:165311
DSSTox Substance ID:DTXSID00304292
Wikidata:Q82050124
Mol file:29571-44-6.mol

Synonyms:29571-44-6;ethyl 2-(2-(methylthio)-6-oxo-1,6-dihydropyrimidin-5-yl)acetate;ETHYL 2-(4-HYDROXY-2-(METHYLTHIO)PYRIMIDIN-5-YL)ACETATE;ethyl 2-(2-methylsulfanyl-6-oxo-1H-pyrimidin-5-yl)acetate;5-Pyrimidineaceticacid, 3,4-dihydro-2-(methylthio)-4-oxo-, ethyl ester;5-PYRIMIDINEACETIc acid,3,4-DIHYDRO-2-(METHYLTHIO)-4-OXO-,ETHYL ESTER;ethyl 2-[4-hydroxy-2-(methylthio)pyrimidin-5-yl]acetate;NSC165311;SCHEMBL9298613;SCHEMBL16580714;DTXSID00304292;GKBOFJXGVIZNBD-UHFFFAOYSA-N;Ethyl2-(2-(methylthio)-6-oxo-1,6-dihydropyrimidin-5-yl)acetate;MFCD11977459;AKOS015838729;AKOS037644793;NSC-165311;SB59986;AM805779;AS-54820;CS-0140420;FT-0651563;W10288;ethyl 2-methylthio-4-hydroxy-pyrimidine-5-acetate;ethyl [2-(methylsulfanyl)-6-oxo-1,6-dihydropyrimidin-5-yl]acetate

Suppliers and Price of Ethyl 2-(2-(methylthio)-6-oxo-1,6-dihydropyrimidin-5-yl)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Ethyl2-(2-(Methylthio)-6-oxo-1,6-dihydropyrimidin-5-yl)acetate
100mg
$ 155.00

TRC
Ethyl2-(2-(Methylthio)-6-oxo-1,6-dihydropyrimidin-5-yl)acetate
10mg
$ 45.00

SynChem
ETHYL 2-(2-(METHYLTHIO)-6-OXO-1,6-DIHYDROPYRIMIDIN-5-YL)ACETATE 95%
1 g
$ 289.00

Crysdot
Ethyl2-(2-(methylthio)-6-oxo-1,6-dihydropyrimidin-5-yl)acetate 95+%
1g
$ 301.00

Crysdot
Ethyl2-(2-(methylthio)-6-oxo-1,6-dihydropyrimidin-5-yl)acetate 95+%
5g
$ 903.00

Chemenu
ethyl2-(2-(methylthio)-6-oxo-1,6-dihydropyrimidin-5-yl)acetate 95%
1g
$ 284.00

Chemenu
ethyl2-(2-(methylthio)-6-oxo-1,6-dihydropyrimidin-5-yl)acetate 95%
5g
$ 852.00

American Custom Chemicals Corporation
ETHYL-2-(2-(METHYLTHIO)-6-OXO-1,6-DIHYDROPYRIMIDIN-5-YL)ACETATE 95.00%
5MG
$ 505.74

Total 9 raw suppliers

Chemical Property of Ethyl 2-(2-(methylthio)-6-oxo-1,6-dihydropyrimidin-5-yl)acetate

Chemical Property:

Vapor Pressure:2.67E-06mmHg at 25°C
Melting Point:188-189℃
Boiling Point:379.5°C at 760 mmHg
Flash Point:183.3°C
PSA：97.35000
Density:1.32g/cm³
LogP:0.59740
Storage Temp.:2-8°C
XLogP3:0.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:228.05686342
Heavy Atom Count:15
Complexity:336

Purity/Quality:

97% ^*data from raw suppliers

Ethyl2-(2-(Methylthio)-6-oxo-1,6-dihydropyrimidin-5-yl)acetate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)CC1=CN=C(NC1=O)SC

Technology Process of Ethyl 2-(2-(methylthio)-6-oxo-1,6-dihydropyrimidin-5-yl)acetate

There total 6 articles about Ethyl 2-(2-(methylthio)-6-oxo-1,6-dihydropyrimidin-5-yl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 4338-95-8
S-methylthiouronium iodide

: 5472-38-8
diethyl 2-formylbutanedioate

: 29571-44-6
ethyl 2-[4-hydroxy-2-(methylthio)pyrimidin-5-yl]acetate

Guidance literature:: diethyl 2-formylbutanedioate; With sodium ethanolate; In ethanol; at 0 ℃; for 0.0833333h; Inert atmosphere;

S-methylthiouronium iodide; In ethanol; at 0 - 20 ℃; for 48h; Inert atmosphere;

With hydrogenchloride; In ethanol; water; at 20 ℃; for 0.5h; Inert atmosphere;
DOI:10.1007/s00706-015-1634-1

Reference yield: 50.0%

: 147895-43-0
S-methylisothiourea hemisulphate

: 5472-38-8
diethyl 2-formylbutanedioate

: 29571-44-6
ethyl 2-[4-hydroxy-2-(methylthio)pyrimidin-5-yl]acetate

Guidance literature:: S-methylisothiourea hemisulphate; diethyl 2-formylbutanedioate; With sodium hydroxide; In water; at 100 ℃; for 1.5h;

With acetic acid; In water; at 20 ℃; for 0.25h;