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5472-38-8

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5472-38-8 Usage

Description

DIETHYL FORMYLSUCCINATE, with the molecular formula C9H16O4, is a clear, colorless liquid chemical compound. It serves as a versatile reagent in organic synthesis, particularly for the preparation of a variety of organic compounds. As a formylating agent, it introduces the formyl group (-CHO) into organic molecules, making it a valuable intermediate in the synthesis of pharmaceuticals, agrochemicals, and fine chemicals. Furthermore, its applications extend to the production of fragrances, flavoring agents, polymers, and plastics. Due to its potential hazards, it is crucial to handle DIETHYL FORMYLSUCCINATE with care and adhere to proper safety protocols.

Uses

Used in Organic Synthesis:
DIETHYL FORMYLSUCCINATE is used as a reagent for the preparation of various organic compounds, facilitating the introduction of the formyl group into organic molecules.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, DIETHYL FORMYLSUCCINATE is used as an intermediate in the synthesis of various pharmaceuticals, contributing to the development of new drugs and medications.
Used in Agrochemical Production:
DIETHYL FORMYLSUCCINATE plays a role in the synthesis of agrochemicals, serving as an intermediate in the production of compounds used in agriculture to protect crops and enhance yields.
Used in Fine Chemicals Synthesis:
DIETHYL FORMYLSUCCINATE is utilized as an intermediate in the synthesis of fine chemicals, which are high-purity chemicals used in various specialized applications.
Used in Fragrance and Flavor Production:
DIETHYL FORMYLSUCCINATE is used in the production of fragrances and flavoring agents, adding to the sensory characteristics of various consumer products.
Used in Polymer and Plastics Manufacturing:
It is also employed in the manufacturing of polymers and plastics, contributing to the development of materials with specific properties for diverse applications.

Check Digit Verification of cas no

The CAS Registry Mumber 5472-38-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,7 and 2 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 5472-38:
(6*5)+(5*4)+(4*7)+(3*2)+(2*3)+(1*8)=98
98 % 10 = 8
So 5472-38-8 is a valid CAS Registry Number.
InChI:InChI=1/C9H14O5/c1-3-13-8(11)5-7(6-10)9(12)14-4-2/h6-7H,3-5H2,1-2H3

5472-38-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name diethyl 2-formylbutanedioate

1.2 Other means of identification

Product number -
Other names diethyl formylsuccinate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5472-38-8 SDS

5472-38-8Relevant articles and documents

1 Methyl 3 piperidone and 1 methyl 3 pyrrolidone derivatives from a Dieckmann reaction

Nichols,Barfknecht

, p. 339 - 341 (1973)

-

CYCLIN-DEPENDENT KINASE INHIBITORS

-

Page/Page column 268-269, (2020/07/15)

Described herein are compounds and their pharmaceutically acceptable salts, pharmaceutical compositions thereof, methods of treatment, and medical uses. The compounds described herein are modulators of cyclin-dependent kinases, and are useful in the treatment or alleviation of protein kinase associated disorders, including cancer, infectious diseases, autoimmune diseases, or cardiovascular diseases.

Synthesis and in?vitro evaluation of new fluorinated quinoline derivatives with high affinity for PDE5: Towards the development of new PET neuroimaging probes

Liu, Jianrong,Maisonial-Besset, Aurélie,Wenzel, Barbara,Canitrot, Damien,Baufond, Ariane,Chezal, Jean-Michel,Brust, Peter,Moreau, Emmanuel

, p. 548 - 560 (2017/05/24)

The increasing incidence of Alzheimer's disease (AD) worldwide is a major public health problem. Current treatments provide only palliative solutions with significant side effects. Therefore, new efficient treatment options and novel early diagnosis tools are urgently needed. Recently, strong pre-clinical evidences suggested that phosphodiesterase 5 (PDE5) may be clinically relevant both as biomarker and drug-target in AD. In this study, we intended to develop a new radiofluorinated tracer for the visualisation of PDE5 in brain using PET imaging. Based on currently known PDE5 inhibitors, a series of novel fluorinated compounds bearing a quinoline core have been synthesised via multi-steps reaction pathways. Their affinity for PDE5 and selectivity over other PDE families have been investigated. According to the data collected from this in vitro screening, fluorinated derivatives 24a, b bearing a fluoroethoxy group at the C-3 position of the quinoline core appeared to be the most promising structures and will be further radiolabelled with fluorine-18 for in vitro and in vivo evaluations as PET radiotracer for neuroimaging of PDE5.

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