Cyclohexanepropanamide, N-phenyl-

Base Information

• Chemical Name: Cyclohexanepropanamide, N-phenyl-
• CAS No.: 4361-30-2
• Molecular Formula: C15H21NO
• Molecular Weight: 231.338
• Mol file: 4361-30-2.mol

Synonyms:

Chemical Property of Cyclohexanepropanamide, N-phenyl-

Chemical Property:

• PSA: 0.00000
• LogP: 0.00000

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Cyclohexanepropanamide, N-phenyl-

There total 10 articles about Cyclohexanepropanamide, N-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

cyclohexane (110-82-7,25012-93-5) + N-acryloylaniline (2210-24-4) → 3-cyclohexyl-N-(3-phenyl)propanamide (4361-30-2)

Guidance literature:

With iron(III) chloride hexahydrate; In acetonitrile; at 25 ℃; for 14h; Inert atmosphere; UV-irradiation;

DOI:10.1039/d1gc01563j

Reference yield: 92.0%

Acetanilid (103-84-4) + cyclohexylmethyl alcohol (100-49-2) → 3-cyclohexyl-N-(3-phenyl)propanamide (4361-30-2)

Guidance literature:

With tri-tert-butyl phosphine; potassium tert-butylate; nickel diacetate; In 1,4-dioxane; toluene; at 80 ℃; for 12h; Inert atmosphere; Glovebox; Schlenk technique;

DOI:10.1039/d0cc06468h

Reference yield: 83.0%

N-acryloylaniline (2210-24-4) + 1,3-dioxoisoindolin-2-yl cyclohexanecarboxylate (126812-30-4) → 3-cyclohexyl-N-(3-phenyl)propanamide (4361-30-2)

Guidance literature:

With 4-trifluoromethylbenzenethiol; diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; caesium carbonate; In N,N-dimethyl-formamide; at 25 ℃; for 4h; Schlenk technique; Inert atmosphere; Irradiation;

DOI:10.1021/acs.orglett.6b03300

upstream raw materials:

3-cyclohexylpropanamide

vinylcyclohexane

phenyl isocyanate

cyclohexanepropionic acid