L-Leucine, glycyl-L-phenylalanyl-, methyl ester

Base Information

Chemical Name:L-Leucine, glycyl-L-phenylalanyl-, methyl ester
CAS No.:4368-66-5
Molecular Formula:C18H27N3O4
Molecular Weight:349.43
Hs Code.:
DSSTox Substance ID:DTXSID401241685

Synonyms:DTXSID401241685;L-Leucine, glycyl-L-phenylalanyl-, methyl ester;4368-66-5

Suppliers and Price of L-Leucine, glycyl-L-phenylalanyl-, methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of L-Leucine, glycyl-L-phenylalanyl-, methyl ester

Chemical Property:

XLogP3:0.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:10
Exact Mass:349.20015635
Heavy Atom Count:25
Complexity:448

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)CC(C(=O)OC)NC(=O)C(CC1=CC=CC=C1)NC(=O)CN
Isomeric SMILES:CC(C)C[C@@H](C(=O)OC)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)CN

Technology Process of L-Leucine, glycyl-L-phenylalanyl-, methyl ester

There total 7 articles about L-Leucine, glycyl-L-phenylalanyl-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 3982-71-6
N-benzyloxycarbonylglycyl-L-phenylalanyl-L-leucine methyl ester

: 4368-66-5
glycyl-L-phenylalanyl-L-leucine methyl ester

Guidance literature:: acidic hydrogenolysis;
DOI:10.1016/S0040-4039(00)82132-2

Reference yield:

: Boc-Gly-Phe-Leu-OMe

: 4368-66-5
glycyl-L-phenylalanyl-L-leucine methyl ester

Guidance literature:: With hydrogenchloride; In tetrahydrofuran;

Reference yield:

: 2666-93-5
(S)-Leu-OMe

: 4368-66-5
glycyl-L-phenylalanyl-L-leucine methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: DCC, HOBT / dimethylformamide

2: HCl / tetrahydrofuran

With hydrogenchloride; benzotriazol-1-ol; dicyclohexyl-carbodiimide; In tetrahydrofuran; N,N-dimethyl-formamide;