2,4-Pentadienoyl chloride, 5-[4-(trifluoromethyl)phenyl]-, (2E,4E)-

Base Information

Chemical Name:2,4-Pentadienoyl chloride, 5-[4-(trifluoromethyl)phenyl]-, (2E,4E)-
CAS No.:443360-65-4
Molecular Formula:C12H8ClF3O
Molecular Weight:260.643
Hs Code.:

Synonyms:

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Chemical Property of 2,4-Pentadienoyl chloride, 5-[4-(trifluoromethyl)phenyl]-, (2E,4E)-

Chemical Property:

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Technology Process of 2,4-Pentadienoyl chloride, 5-[4-(trifluoromethyl)phenyl]-, (2E,4E)-

There total 1 articles about 2,4-Pentadienoyl chloride, 5-[4-(trifluoromethyl)phenyl]-, (2E,4E)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 443360-58-5
methyl (2E,4E)-5-((p-(trifluoromethyl))phenyl)penta-2,4-dienoate

: 443360-65-4
(2E,4E)-5-(4-Trifluoromethyl-phenyl)-penta-2,4-dienoyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: aq. KOH / methanol / 22 h / 20 °C

2: SOCl₂ / 3 h / 70 °C

With potassium hydroxide; thionyl chloride; In methanol;
DOI:10.1021/jm020350r

Reference yield:

: 443360-65-4
(2E,4E)-5-(4-Trifluoromethyl-phenyl)-penta-2,4-dienoyl chloride

: (2S,5S)-8-[5-[4-(trifluoromethyl)phenyl]pentanoylamino]benzolactam V

Guidance literature:: Multi-step reaction with 2 steps

1: Et₃N / tetrahydrofuran / 4 h / 20 °C

2: 90 percent / H₂ / Pd/C / 3 h / 20 °C

With hydrogen; triethylamine; palladium on activated charcoal; In tetrahydrofuran;
DOI:10.1021/jm020350r