Benzenesulfonyl chloride, 4-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-

Base Information

Chemical Name:Benzenesulfonyl chloride, 4-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-
CAS No.:4435-59-0
Molecular Formula:C14H8ClNO4S
Molecular Weight:321.741
Hs Code.:
DSSTox Substance ID:DTXSID40541563
Nikkaji Number:J3.309.924J
Wikidata:Q82417945

Synonyms:4435-59-0;Benzenesulfonyl chloride, 4-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-;SCHEMBL2416456;DTXSID40541563;LHLPYYKEYVGQFE-UHFFFAOYSA-N;AKOS000161004;J-100229;4-(1,3-dioxoisoindolin-2-yl)-benzene-1-sulfonyl chloride;4-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)benzene-1-sulfonyl chloride

Suppliers and Price of Benzenesulfonyl chloride, 4-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Benzenesulfonyl chloride, 4-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:320.9862566
Heavy Atom Count:21
Complexity:524

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=O)N(C2=O)C3=CC=C(C=C3)S(=O)(=O)Cl

Technology Process of Benzenesulfonyl chloride, 4-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-

There total 7 articles about Benzenesulfonyl chloride, 4-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 520-03-6
N-phenylphthalimide

: 4435-59-0
4-(1,3-dioxo-2,3-dihydro-1H-2-isoindolyl)-1-benzenesulfonyl chloride

Guidance literature:: With chlorosulfonic acid; at 30 - 75 ℃; for 2h;

Reference yield: 77.0%

: 86581-47-7
4-(1,3-dioxoisoindolin-2-yl)benzenesulfonic acid

: 4435-59-0
4-(1,3-dioxo-2,3-dihydro-1H-2-isoindolyl)-1-benzenesulfonyl chloride

Guidance literature:: With thionyl chloride; In N,N-dimethyl-formamide; at 20 ℃; for 2h;

Reference yield:

: 85-44-9
phthalic anhydride

: 4435-59-0
4-(1,3-dioxo-2,3-dihydro-1H-2-isoindolyl)-1-benzenesulfonyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: 3 h / 130 °C

2: chlorosulfonic acid; phosphorus trichloride / 0.75 h / 50 °C

With chlorosulfonic acid; phosphorus trichloride;
DOI:10.1021/jm300602n