Carbamic acid, dimethyl-, 4-[1-[[(1,1-dimethylethoxy)carbonyl]methylamino]-4-hydroxybutyl]phenyl ester

Base Information

Chemical Name:Carbamic acid, dimethyl-, 4-[1-[[(1,1-dimethylethoxy)carbonyl]methylamino]-4-hydroxybutyl]phenyl ester
CAS No.:444646-46-2
Molecular Formula:C19H30N2O5
Molecular Weight:366.458
Hs Code.:

Synonyms:

Suppliers and Price of Carbamic acid, dimethyl-, 4-[1-[[(1,1-dimethylethoxy)carbonyl]methylamino]-4-hydroxybutyl]phenyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Carbamic acid, dimethyl-, 4-[1-[[(1,1-dimethylethoxy)carbonyl]methylamino]-4-hydroxybutyl]phenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Carbamic acid, dimethyl-, 4-[1-[[(1,1-dimethylethoxy)carbonyl]methylamino]-4-hydroxybutyl]phenyl ester

There total 13 articles about Carbamic acid, dimethyl-, 4-[1-[[(1,1-dimethylethoxy)carbonyl]methylamino]-4-hydroxybutyl]phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 79-44-7
N,N-Dimethylcarbamoyl chloride

: 444646-45-1
t-butyl N-[4-hydroxybutyl-1-(4-hydroxyphenyl)]-N-methylcarbamate

: 444646-46-2
N-[1-(4-dimethylcarbamoyloxyphenyl)-4-hydroxybutyl]-N-methylcarbamic acid tert-butyl ester

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 12h;

Reference yield:

: 123-08-0,65581-83-1
4-hydroxy-benzaldehyde

: 444646-46-2
N-[1-(4-dimethylcarbamoyloxyphenyl)-4-hydroxybutyl]-N-methylcarbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 13 steps

1.1: ethanol / 2 h / 90 °C

2.1: sulfuric acid / 6 h / 80 °C

3.1: tetrahydrofuran / 12 h / 20 °C

4.1: K₂CO₃ / dimethylformamide / 3 h / 20 °C

5.1: LiAlH₄ / tetrahydrofuran / 0.17 h / -20 - -10 °C

6.1: 2.20 g / NaOH / H₂O; methanol / 2 h / 50 °C

7.1: 1.90 g / K₂CO₃ / acetone / 2 h / 50 °C

8.1: 2.24 g / Et₃N / tetrahydrofuran / 1 h / 20 °C

9.1: 1.54 g / 15-crown-5 / dimethylformamide / 12 h / 20 °C

10.1: diisobutylaluminium hydride / CH₂Cl₂; hexane / 2 h / -78 - 20 °C

10.2: NH₄Cl / H₂O

11.1: 351 mg / NaBH₄ / methanol / 0.33 h / 20 °C

12.1: 274 mg / H₂ / 5 percent Pd/C / methanol / 4 h / 20 °C

13.1: 256 mg / K₂CO₃ / dimethylformamide / 12 h / 20 °C

With sodium hydroxide; sodium tetrahydroborate; lithium aluminium tetrahydride; 15-crown-5; sulfuric acid; hydrogen; diisobutylaluminium hydride; potassium carbonate; triethylamine; palladium on activated charcoal; In tetrahydrofuran; methanol; ethanol; hexane; dichloromethane; water; N,N-dimethyl-formamide; acetone;

Reference yield:

: 10303-89-6
3-(4-hydroxy-phenyl)-3-methylamino-propionic acid

: 444646-46-2
N-[1-(4-dimethylcarbamoyloxyphenyl)-4-hydroxybutyl]-N-methylcarbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 12 steps

1.1: sulfuric acid / 6 h / 80 °C

2.1: tetrahydrofuran / 12 h / 20 °C

3.1: K₂CO₃ / dimethylformamide / 3 h / 20 °C

4.1: LiAlH₄ / tetrahydrofuran / 0.17 h / -20 - -10 °C

5.1: 2.20 g / NaOH / H₂O; methanol / 2 h / 50 °C

6.1: 1.90 g / K₂CO₃ / acetone / 2 h / 50 °C

7.1: 2.24 g / Et₃N / tetrahydrofuran / 1 h / 20 °C

8.1: 1.54 g / 15-crown-5 / dimethylformamide / 12 h / 20 °C

9.1: diisobutylaluminium hydride / CH₂Cl₂; hexane / 2 h / -78 - 20 °C

9.2: NH₄Cl / H₂O

10.1: 351 mg / NaBH₄ / methanol / 0.33 h / 20 °C

11.1: 274 mg / H₂ / 5 percent Pd/C / methanol / 4 h / 20 °C

12.1: 256 mg / K₂CO₃ / dimethylformamide / 12 h / 20 °C

With sodium hydroxide; sodium tetrahydroborate; lithium aluminium tetrahydride; 15-crown-5; sulfuric acid; hydrogen; diisobutylaluminium hydride; potassium carbonate; triethylamine; palladium on activated charcoal; In tetrahydrofuran; methanol; hexane; dichloromethane; water; N,N-dimethyl-formamide; acetone;