Chemical Property of Brincidofovir
Chemical Property:
- Melting Point:> 177° C (dec.)
- Boiling Point:688.6±65.0 °C(Predicted)
- PKA:2.40±0.10(Predicted)
- PSA：156.93000
- Density:1.17±0.1 g/cm3(Predicted)
- LogP:5.59290
- Storage Temp.:Hygroscopic, -20°C Freezer, Under inert atmosphere
- Solubility.:DMSO (Slightly, Sonicated), Ethanol (Slightly, Heated, Sonicated), Methanol (Sli
- XLogP3:4.9
- Hydrogen Bond Donor Count:3
- Hydrogen Bond Acceptor Count:7
- Rotatable Bond Count:26
- Exact Mass:561.35428800
- Heavy Atom Count:38
- Complexity:721
- Purity/Quality:
-
99%, *data from raw suppliers
Brincidofovir *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
-
SDS file from LookChem
Useful:
- Drug Classes:Antiviral Agents
- Canonical SMILES:CCCCCCCCCCCCCCCCOCCCOP(=O)(COC(CN1C=CC(=NC1=O)N)CO)O
- Isomeric SMILES:CCCCCCCCCCCCCCCCOCCCOP(=O)(CO[C@@H](CN1C=CC(=NC1=O)N)CO)O
- Recent ClinicalTrials:Study to Confirm of the Safety and Tolerability of Brincidofovir in Subjects With BK Virus Infection (Viremia) After Kidney Transplantation
- Recent EU Clinical Trials:A Randomized, Controlled, Open-Label, Multiple Ascending Dose Study of Intravenous Brincidofovir in Adult Allogeneic Hematopoietic Cell Transplant Recipients with Adenovirus Viremia
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Uses
Brincidofovir is an antiviral inhibitor, working against BK polymavirus replication in primary human urothelial cells. Cytostatic, cytotoxic agent.
