4-(4-Chlorophenyl)piperidine-4-carboxylic acid ethyl ester

Base Information

Chemical Name:4-(4-Chlorophenyl)piperidine-4-carboxylic acid ethyl ester
CAS No.:46850-22-0
Molecular Formula:C14H18ClNO2
Molecular Weight:267.755
Hs Code.:
DSSTox Substance ID:DTXSID00596332
Wikidata:Q82491560
Mol file:46850-22-0.mol

Synonyms:46850-22-0;4-(4-CHLOROPHENYL)PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER;ethyl 4-(4-chlorophenyl)piperidine-4-carboxylate;SCHEMBL4873297;DTXSID00596332;XWXPGOVBYIYZAU-UHFFFAOYSA-N;DB-308005;4-(p-chlorophenyl)-4-ethoxycarbonylpiperidine;4-(4-chlorophenyl)-4-piperidinecarboxylic acid ethyl ester;4-(4-Chloro-phenyl)-piperidine-4-carboxylic acid ethyl ester

Suppliers and Price of 4-(4-Chlorophenyl)piperidine-4-carboxylic acid ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 4-(4-Chlorophenyl)piperidine-4-carboxylic acid ethyl ester

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:267.1026065
Heavy Atom Count:18
Complexity:282

Purity/Quality:: 99% ，98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1(CCNCC1)C2=CC=C(C=C2)Cl

Technology Process of 4-(4-Chlorophenyl)piperidine-4-carboxylic acid ethyl ester

There total 2 articles about 4-(4-Chlorophenyl)piperidine-4-carboxylic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 46850-22-0
4-(4-chlorophenyl)-4-piperidinecarboxylic acid ethyl ester

Guidance literature:

Reference yield: 74.0%

: 4-(4-chloro-phenyl)-piperidine-4-carboxylic acid hydrochloride

: 64-17-5
ethanol

: 46850-22-0
4-(4-chlorophenyl)-4-piperidinecarboxylic acid ethyl ester

Guidance literature:: 4-(4-chloro-phenyl)-piperidine-4-carboxylic acid hydrochloride; ethanol; With sulfuric acid; for 71h; Heating / reflux;

With sodium hydrogencarbonate; In ethanol; water;

Reference yield: 88.0%

: 46850-22-0
4-(4-chlorophenyl)-4-piperidinecarboxylic acid ethyl ester

: 672927-27-4
[4-(4-chloro-phenyl)-piperidin-4-yl]-methanol

Guidance literature:: 4-(4-chlorophenyl)-4-piperidinecarboxylic acid ethyl ester; With lithium triethylborohydride; In tetrahydrofuran; diethyl ether; at 20 ℃; for 1h;

With hydrogenchloride; water; In tetrahydrofuran; diethyl ether; at 20 ℃; for 3h;

With sodium hydrogencarbonate; In water;