3-(2-CARBOXY-ETHYL)-INDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

Base Information

Chemical Name:3-(2-CARBOXY-ETHYL)-INDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
CAS No.:468721-38-2
Molecular Formula:C16H19NO4
Molecular Weight:289.331
Hs Code.:
Mol file:468721-38-2.mol

Synonyms:3-(2-CARBOXY-ETHYL)-INDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;3-{1-[(tert-butoxy)carbonyl]-1H-indol-3-yl}propionic acid;1H-Indole-3-propanoic acid,1-[(1,1-dimethylethoxy)carbonyl];3-(1-(TERT-BUTOXYCARBONYL)-1H-INDOL-3-YL)PROPANOIC ACID;

Suppliers and Price of 3-(2-CARBOXY-ETHYL)-INDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Ambeed
3-{1-[(tert-butoxy)carbonyl]-1H-indol-3-yl}propanoicacid 90%
1g
$ 611.00

Ambeed
3-{1-[(tert-butoxy)carbonyl]-1H-indol-3-yl}propanoicacid 90%
250mg
$ 245.00

Ambeed
3-{1-[(tert-butoxy)carbonyl]-1H-indol-3-yl}propanoicacid 90%
100mg
$ 155.00

Ambeed
3-{1-[(tert-butoxy)carbonyl]-1H-indol-3-yl}propanoicacid 90%
50mg
$ 124.00

Total 1 raw suppliers

Chemical Property of 3-(2-CARBOXY-ETHYL)-INDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

Chemical Property:

PSA：68.53000
LogP:3.44170

Purity/Quality:: 3-{1-[(tert-butoxy)carbonyl]-1H-indol-3-yl}propanoicacid 90% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-(2-CARBOXY-ETHYL)-INDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

There total 8 articles about 3-(2-CARBOXY-ETHYL)-INDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 253605-13-9
methyl 3-{1-[(tert-butoxy)carbonyl]-1H-indol-3-yl}propionate

: 468721-38-2
3-{1-[(tert-butoxy)carbonyl]-1H-indol-3-yl}propionic acid

Guidance literature:: With lithium hydroxide; In tetrahydrofuran; water; at 20 ℃; for 9h;
DOI:10.1002/1522-2675(200206)85:6<1567::AID-HLCA1567>3.0.CO;2-T

Reference yield:

: 945679-26-5
3-(2-ethoxycarbonyl-ethyl)-indole-1-carboxylic acid tert-butyl ester

: 468721-38-2
3-{1-[(tert-butoxy)carbonyl]-1H-indol-3-yl}propionic acid

Guidance literature:: With lithium hydroxide; In tetrahydrofuran;
DOI:10.1016/j.bmcl.2005.06.027

Reference yield:

: 5548-09-4
Methyl indole-3-propionate

: 468721-38-2
3-{1-[(tert-butoxy)carbonyl]-1H-indol-3-yl}propionic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 92 percent / DMAP / acetonitrile / 2.5 h / 20 °C

2: 94 percent / LiOH*H₂O / tetrahydrofuran; H₂O / 9 h / 20 °C

With dmap; lithium hydroxide; In tetrahydrofuran; water; acetonitrile;
DOI:10.1002/1522-2675(200206)85:6<1567::AID-HLCA1567>3.0.CO;2-T