4-(2,5-Difluorophenyl)-4-((4-(trifluoromethyl)phenyl)sulfonyl)cyclohexanone

Base Information

Chemical Name:4-(2,5-Difluorophenyl)-4-((4-(trifluoromethyl)phenyl)sulfonyl)cyclohexanone
CAS No.:471903-60-3
Molecular Formula:C19H15F5O3S
Molecular Weight:418.384
Hs Code.:2914700090
DSSTox Substance ID:DTXSID701144046
Mol file:471903-60-3.mol

Synonyms:471903-60-3;4-(2,5-DIFLUOROPHENYL)-4-((4-(TRIFLUOROMETHYL)PHENYL)SULFONYL)CYCLOHEXANONE;4-(2,5-Difluorophenyl)-4-[[4-(trifluoromethyl)phenyl]sulfonyl]cyclohexanone;SCHEMBL4397566;DTXSID701144046;4-[(4-trifluoromethylphenyl)sulfonyl]-4-(2,5-difluorophenyl) cyclohexanone;4-[(4-trifluoromethylphenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexanone

Suppliers and Price of 4-(2,5-Difluorophenyl)-4-((4-(trifluoromethyl)phenyl)sulfonyl)cyclohexanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
4-(2,5-Difluorophenyl)-4-((4-(trifluoromethyl)phenyl)sulfonyl)cyclohexanone 95+%
1g
$ 794.00

Alichem
4-(2,5-Difluorophenyl)-4-((4-(trifluoromethyl)phenyl)sulfonyl)cyclohexanone
1g
$ 895.70

Total 0 raw suppliers

Chemical Property of 4-(2,5-Difluorophenyl)-4-((4-(trifluoromethyl)phenyl)sulfonyl)cyclohexanone

Chemical Property:

PSA：59.59000
LogP:5.87670
XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:3
Exact Mass:418.06620632
Heavy Atom Count:28
Complexity:667

Purity/Quality:: 4-(2,5-Difluorophenyl)-4-((4-(trifluoromethyl)phenyl)sulfonyl)cyclohexanone 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(CCC1=O)(C2=C(C=CC(=C2)F)F)S(=O)(=O)C3=CC=C(C=C3)C(F)(F)F

Technology Process of 4-(2,5-Difluorophenyl)-4-((4-(trifluoromethyl)phenyl)sulfonyl)cyclohexanone

There total 1 articles about 4-(2,5-Difluorophenyl)-4-((4-(trifluoromethyl)phenyl)sulfonyl)cyclohexanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 471903-60-3
4-(2,5-difluoro-phneyl)-4-(4-trifluoromethyl-benzenesulfonyl)-cyclohexanone

Guidance literature:

Reference yield: 30.0%

: 471903-60-3
4-(2,5-difluoro-phneyl)-4-(4-trifluoromethyl-benzenesulfonyl)-cyclohexanone

: 76513-69-4
(2-trimethylethylsilylethoxy)methyl chloride

: 793672-79-4
(R,S)-4-[(4-trifluoromethylphenyl)sulfonyl]-4-(2,5-difluorophenyl)-2-[2-(trimethylsilyl)ethoxymethyl]cyclohexanone

Guidance literature:: With n-butyllithium; (1S,1'S)-bis(1-phenylethyl)amine; lithium chloride; In tetrahydrofuran; hexanes; at -100 - 0 ℃; for 1.5h;

4-(2,5-difluoro-phneyl)-4-(4-trifluoromethyl-benzenesulfonyl)-cyclohexanone; In tetrahydrofuran; hexanes; at -100 - -78 ℃; for 2h;

(2-trimethylethylsilylethoxy)methyl chloride; In tetrahydrofuran; hexanes; at -100 - -12 ℃;

Reference yield:

: 471903-60-3
4-(2,5-difluoro-phneyl)-4-(4-trifluoromethyl-benzenesulfonyl)-cyclohexanone

: 556-56-9
allyl iodid

: 793672-94-3
C₂₂H₁₉F₅O₃S

Guidance literature:: With n-butyllithium; (1S,1'S)-bis(1-phenylethyl)amine; lithium chloride; In tetrahydrofuran; hexane; at -100 - -20 ℃; for 2.41667h;

4-(2,5-difluoro-phneyl)-4-(4-trifluoromethyl-benzenesulfonyl)-cyclohexanone; In tetrahydrofuran; hexane; at -100 - -78 ℃; for 0.833333h;

allyl iodid; In tetrahydrofuran; hexane; at -100 - 20 ℃; for 18h;