1-(5-Methyl-1,2-oxazol-3-yl)propan-1-one

Base Information

Chemical Name:1-(5-Methyl-1,2-oxazol-3-yl)propan-1-one
CAS No.:473732-48-8
Molecular Formula:C7H9NO2
Molecular Weight:139.15200
Hs Code.:
European Community (EC) Number:845-021-3
Mol file:473732-48-8.mol

Synonyms:1-(5-methyl-1,2-oxazol-3-yl)propan-1-one;473732-48-8;1-(5-METHYLISOXAZOL-3-YL)PROPAN-1-ONE;SCHEMBL12261481;AMY7737;EN300-2485234

Suppliers and Price of 1-(5-Methyl-1,2-oxazol-3-yl)propan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-(5-METHYLISOXAZOL-3-YL)PROPAN-1-ONE 95.00%
5MG
$ 497.97

AK Scientific
1-(5-Methyl-1,2-oxazol-3-yl)propan-1-one
100mg
$ 407.00

Total 5 raw suppliers

Chemical Property of 1-(5-Methyl-1,2-oxazol-3-yl)propan-1-one

Chemical Property:

PSA：43.10000
LogP:1.57570
XLogP3:1.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:139.063328530
Heavy Atom Count:10
Complexity:136

Purity/Quality:

99% ^*data from raw suppliers

1-(5-METHYLISOXAZOL-3-YL)PROPAN-1-ONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(=O)C1=NOC(=C1)C

Technology Process of 1-(5-Methyl-1,2-oxazol-3-yl)propan-1-one

There total 1 articles about 1-(5-Methyl-1,2-oxazol-3-yl)propan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 173305-19-6
N-methoxy-N,5-dimethylisoxazole-3-carboxamide

: 473732-48-8
1-(5-methylisoxazol-3-yl)propan-1-one

Guidance literature:: ethyl iodide; With tert.-butyl lithium; In diethyl ether; pentane; at -78 - 20 ℃; for 1h;

N-methoxy-N,5-dimethylisoxazole-3-carboxamide; In tetrahydrofuran; diethyl ether; pentane; at -78 - 0 ℃; for 3h;

Reference yield:

: 473732-48-8
1-(5-methylisoxazol-3-yl)propan-1-one

: ethyl 2-((4S,5S)-1-(4-bromophenyl)-4-methyl-3-(5-methylisoxazol-3-yl)-4,5-dihydro-1H-pyrazol-5-yl)acetate

Guidance literature:: Multi-step reaction with 3 steps

1: sodium ethanolate / ethanol / 12 h / 20 °C / Cooling with ice

2: toluene / 2 h / 50 °C

3: trifluoroacetic acid / ethanol / 12 h / 90 °C

With sodium ethanolate; trifluoroacetic acid; In ethanol; toluene;

Reference yield:

: 473732-48-8
1-(5-methylisoxazol-3-yl)propan-1-one

: ethyl 2-((4S,5S)-1-(4-((2'-fluoro-5'-methoxy-3-methyl-[1,1'-biphenyl]-4-yl)methyl)phenyl)-4-methyl-3-(5-methylisoxazol-3-yl)-4,5-dihydro-1H-pyrazol-5-yl)acetate

Guidance literature:: Multi-step reaction with 4 steps

1.1: sodium ethanolate / ethanol / 12 h / 20 °C / Cooling with ice

2.1: toluene / 2 h / 50 °C

3.1: trifluoroacetic acid / ethanol / 12 h / 90 °C

4.1: zinc; ethylene dibromide; chloro-trimethyl-silane / tetrahydrofuran / 2 h / 65 °C / Inert atmosphere

4.2: 6 h / 80 °C / Inert atmosphere

With chloro-trimethyl-silane; sodium ethanolate; ethylene dibromide; trifluoroacetic acid; zinc; In tetrahydrofuran; ethanol; toluene;