Ethanone, 1-cyclopropyl-, O-(3-((1,1-dimethylethyl)amino)-2-hydroxypropyl)oxime, (R-(E))-

Base Information

Chemical Name:Ethanone, 1-cyclopropyl-, O-(3-((1,1-dimethylethyl)amino)-2-hydroxypropyl)oxime, (R-(E))-
CAS No.:96479-87-7
Molecular Formula:C₁₂H₂₄N₂O₂
Molecular Weight:228.335
Hs Code.:
UNII:DNW5G2E6X0
Wikipedia:Falintolol
Wikidata:Q27274679
NCI Thesaurus Code:C73016
ChEMBL ID:CHEMBL171059
Mol file:96479-87-7.mol

Synonyms:falintolol;falintolol oxalate, anti-(R);falintolol oxalate, anti-(S);falintolol oxalate, syn(R);falintolol oxalate, syn-(S);falintolol, anti-(S);falintolol, syn-(R);falintolol, syn-(S);O-(3-(tert-butylamino)-2-hydroxypropyl)cyclopropyl methyl ketone oxime

Suppliers and Price of Ethanone, 1-cyclopropyl-, O-(3-((1,1-dimethylethyl)amino)-2-hydroxypropyl)oxime, (R-(E))-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of Ethanone, 1-cyclopropyl-, O-(3-((1,1-dimethylethyl)amino)-2-hydroxypropyl)oxime, (R-(E))-

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:343.6°Cat760mmHg
PKA:14.32±0.20(Predicted)
Flash Point:161.6°C
PSA：53.85000
Density:1.07g/cm³
LogP:1.92880
XLogP3:0.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:228.183778013
Heavy Atom Count:16
Complexity:242

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=NOCC(CNC(C)(C)C)O)C1CC1
Isomeric SMILES:C/C(=N\OC[C@@H](CNC(C)(C)C)O)/C1CC1

Technology Process of Ethanone, 1-cyclopropyl-, O-(3-((1,1-dimethylethyl)amino)-2-hydroxypropyl)oxime, (R-(E))-

There total 9 articles about Ethanone, 1-cyclopropyl-, O-(3-((1,1-dimethylethyl)amino)-2-hydroxypropyl)oxime, (R-(E))- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 51761-72-9
cyclopropyl methyl ketone oxime

: 88134-91-2,90581-63-8,96479-87-7
Falintolol

Guidance literature:: Multi-step reaction with 2 steps

1: NaH / tetrahydrofuran / 48 h / Ambient temperature

2: ethanol / 24 h / Ambient temperature

With sodium hydride; In tetrahydrofuran; ethanol;
DOI:10.1021/jm00376a011