hydron;N-methyl-3-(2-methylphenoxy)-3-phenylpropan-1-amine;chloride

Base Information

Chemical Name:hydron;N-methyl-3-(2-methylphenoxy)-3-phenylpropan-1-amine;chloride
CAS No.:82857-40-7
Molecular Formula:C₁₇H₂₁NO*ClH
Molecular Weight:291.821
Hs Code.:

Synonyms:AKOS026749968;PD065521

Suppliers and Price of hydron;N-methyl-3-(2-methylphenoxy)-3-phenylpropan-1-amine;chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
rac Atomoxetine Hydrochloride
5mg
$ 446.00

TRC
racAtomoxetineHydrochloride
10mg
$ 265.00

TRC
racAtomoxetineHydrochloride
50mg
$ 1110.00

American Custom Chemicals Corporation
N-METHYL-GAMMA-(2-METHYL-PHENOXY)BENZENEPROPANAMINE 95.00%
50MG
$ 1904.02

American Custom Chemicals Corporation
N-METHYL-GAMMA-(2-METHYL-PHENOXY)BENZENEPROPANAMINE 95.00%
5MG
$ 749.60

Total 12 raw suppliers

Chemical Property of hydron;N-methyl-3-(2-methylphenoxy)-3-phenylpropan-1-amine;chloride

Chemical Property:

Melting Point:124-126°C
PSA：21.26000
LogP:4.91750
Storage Temp.:Refrigerator
Solubility.:Chloroform (Slightly), Methanol (Slightly)
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:291.1389920
Heavy Atom Count:20
Complexity:237

Purity/Quality:

97% ^*data from raw suppliers

rac Atomoxetine Hydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:[H+].CC1=CC=CC=C1OC(CCNC)C2=CC=CC=C2.[Cl-]
Uses Rac Atomoxetine Hydrochloride is a compound active at novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases.

Technology Process of hydron;N-methyl-3-(2-methylphenoxy)-3-phenylpropan-1-amine;chloride

There total 44 articles about hydron;N-methyl-3-(2-methylphenoxy)-3-phenylpropan-1-amine;chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.8%

: 105314-52-1,105314-53-2,63940-51-2,83015-26-3
(R)-tomoxetine

: 82248-59-7,82857-40-7
atomoxetine hydrochloride

Guidance literature:: With hydrogenchloride; In diethyl ether;
DOI:10.1016/j.tet.2004.12.059

Reference yield: 99.0%

: 615-37-2
ortho-methylphenyl iodide

: 115290-81-8
(R)-N-methyl-3-phenyl-3-hydroxypropylamine

: 82248-59-7,82857-40-7
atomoxetine hydrochloride

Guidance literature:: ortho-methylphenyl iodide; (R)-N-methyl-3-phenyl-3-hydroxypropylamine; With potassium carbonate; copper(l) iodide; In toluene; at 148 ℃; for 21h; Heating / reflux;

With hydrogenchloride; In water; pH=1 - 2;

With sodium hydroxide; In water; pH=11 - 12;

Reference yield: 97.0%

: 83113-55-7
(R)-tomoxetine (S)-(+)-mandelate

: 82248-59-7,82857-40-7
atomoxetine hydrochloride

Guidance literature:: (R)-tomoxetine (S)-(+)-mandelate; In ethyl acetate; at 20 ℃; Heating / reflux;

With hydrogenchloride; In acetic acid butyl ester; at 15 - 20 ℃; for 2h; Product distribution / selectivity;