8-benzyl-1-(4-fluorophenyl)-1,3,8-triazaspiro[4,5]decan-4-one

Base Information

Chemical Name:8-benzyl-1-(4-fluorophenyl)-1,3,8-triazaspiro[4,5]decan-4-one
CAS No.:85098-78-8
Molecular Formula:C20H22 F N3 O
Molecular Weight:339.413
Hs Code.:
Mol file:85098-78-8.mol

Synonyms:8-benzyl-1-(4-fluorophenyl)-1,3,8-triazaspiro[4,5]decan-4-one

Suppliers and Price of 8-benzyl-1-(4-fluorophenyl)-1,3,8-triazaspiro[4,5]decan-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 5 raw suppliers

Chemical Property of 8-benzyl-1-(4-fluorophenyl)-1,3,8-triazaspiro[4,5]decan-4-one

Chemical Property:

PSA：39.07000
LogP:3.03300

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 8-benzyl-1-(4-fluorophenyl)-1,3,8-triazaspiro[4,5]decan-4-one

There total 6 articles about 8-benzyl-1-(4-fluorophenyl)-1,3,8-triazaspiro[4,5]decan-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 167263-29-8
8-benzyl-1-(4-fluoro-phenyl)-1,3,8-triaza-spiro[4.5]dec-2-en-4-one

: 85098-78-8
8-benzyl-1-(4-fluoro-phenyl)-1,3,8-triaza-spiro[4.5]decan-4-one

Guidance literature:: With sodium tetrahydroborate; In methanol; at 20 ℃; for 2h;
DOI:10.1021/acs.jmedchem.8b00278

Reference yield: 84.0%

: 85098-78-8
8-benzyl-1-(4-fluoro-phenyl)-1,3,8-triaza-spiro[4.5]decan-4-one

Guidance literature:: With methanol; sodium tetrahydroborate; at 20 ℃; for 2h;

Reference yield:

: 61085-41-4
1-benzyl-4-((4-fluorophenyl)amino)piperidine-4-carboxamide

: 85098-78-8
8-benzyl-1-(4-fluoro-phenyl)-1,3,8-triaza-spiro[4.5]decan-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid / 0.67 h / 170 °C / Microwave irradiation

2: sodium tetrahydroborate; methanol / 4 h / 0 - 25 °C

With methanol; sodium tetrahydroborate; acetic acid;