1-Benzyl-4-((4-fluorophenyl)amino)piperidine-4-carboxamide

Base Information

Chemical Name:1-Benzyl-4-((4-fluorophenyl)amino)piperidine-4-carboxamide
CAS No.:61085-41-4
Molecular Formula:C19H22 F N3 O
Molecular Weight:327.402
Hs Code.:2933399090
European Community (EC) Number:262-586-6
UNII:MS4MQ6FR9F
DSSTox Substance ID:DTXSID20209957
Nikkaji Number:J268.385G
Wikidata:Q83084472
Mol file:61085-41-4.mol

Synonyms:61085-41-4;1-Benzyl-4-((4-fluorophenyl)amino)piperidine-4-carboxamide;MS4MQ6FR9F;EINECS 262-586-6;1-benzyl-4-(4-fluoroanilino)piperidine-4-carboxamide;1-BENZYL-4-[(4-FLUOROPHENYL)AMINO]PIPERIDINE-4-CARBOXAMIDE;UNII-MS4MQ6FR9F;4-((4-Fluorophenyl)amino)-1-(phenylmethyl)-4-piperidinecarboxamide;4-[(4-Fluorophenyl)amino]-1-(phenylmethyl)-4-piperidinecarboxamide;SCHEMBL5556286;DTXSID20209957;DICTXEPQAOBPNR-UHFFFAOYSA-N;1-benzyl-4-(4-fluoro-phenylamino)-piperidine-4-carboxylic acid amide;4-PIPERIDINECARBOXAMIDE, 4-((4-FLUOROPHENYL)AMINO)-1-(PHENYLMETHYL)-

Suppliers and Price of 1-Benzyl-4-((4-fluorophenyl)amino)piperidine-4-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 1-Benzyl-4-((4-fluorophenyl)amino)piperidine-4-carboxamide

Chemical Property:

Vapor Pressure:5.42E-11mmHg at 25°C
Melting Point:162.5 °C
Boiling Point:522°C at 760 mmHg
PKA:15.76±0.20(Predicted)
Flash Point:269.5°C
PSA：59.35000
Density:1.25g/cm³
LogP:3.91830
XLogP3:2.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:327.17469050
Heavy Atom Count:24
Complexity:409

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCC1(C(=O)N)NC2=CC=C(C=C2)F)CC3=CC=CC=C3

Technology Process of 1-Benzyl-4-((4-fluorophenyl)amino)piperidine-4-carboxamide

There total 4 articles about 1-Benzyl-4-((4-fluorophenyl)amino)piperidine-4-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 61085-37-8
1-benzyl-4-((4-fluorophenyl)amino)piperidine-4-carbonitrile

: 61085-41-4
1-benzyl-4-((4-fluorophenyl)amino)piperidine-4-carboxamide

Guidance literature:: With sulfuric acid; at 25 ℃; for 16h;

Reference yield:

: 61085-41-4
1-benzyl-4-((4-fluorophenyl)amino)piperidine-4-carboxamide

Guidance literature:: Nitril 1d, H2SO4;

Reference yield:

: 3612-20-2
1-phenylmethyl-4-piperidone

: 61085-41-4
1-benzyl-4-((4-fluorophenyl)amino)piperidine-4-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid / 18 h / 27 °C / Cooling with ice

2: sulfuric acid / water / 16 h / 27 °C / Cooling with ice

With sulfuric acid; acetic acid; In water;