(4-Hydroxyphenyl)(pyrrolidin-1-yl)methanone

Base Information

Chemical Name:(4-Hydroxyphenyl)(pyrrolidin-1-yl)methanone
CAS No.:478929-28-1
Molecular Formula:C11H13NO2
Molecular Weight:191.22600
Hs Code.:2933990090
DSSTox Substance ID:DTXSID00589527
Wikidata:Q82482954
Mol file:478929-28-1.mol

Synonyms:478929-28-1;(4-hydroxyphenyl)(pyrrolidin-1-yl)methanone;4-(Pyrrolidinocarbonyl)phenol;4-(pyrrolidine-1-carbonyl)phenol;(4-hydroxyphenyl)-pyrrolidin-1-ylmethanone;4-[(pyrrolidin-1-yl)carbonyl]phenol;Pyrrolidine, 1-(4-hydroxybenzoyl)-;SCHEMBL2646078;DTXSID00589527;AKOS000207475;BS-32476;DB-102292;EN300-69105;Z68129365;F2145-0877

Suppliers and Price of (4-Hydroxyphenyl)(pyrrolidin-1-yl)methanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(pyrrolidine-1-carbonyl)phenol
100mg
$ 65.00

AK Scientific
(4-Hydroxyphenyl)(pyrrolidin-1-yl)methanone
100mg
$ 309.00

Total 1 raw suppliers

Chemical Property of (4-Hydroxyphenyl)(pyrrolidin-1-yl)methanone

Chemical Property:

PSA：40.54000
LogP:1.56610
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:191.094628657
Heavy Atom Count:14
Complexity:203

Purity/Quality:: 4-(pyrrolidine-1-carbonyl)phenol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(C1)C(=O)C2=CC=C(C=C2)O

Technology Process of (4-Hydroxyphenyl)(pyrrolidin-1-yl)methanone

There total 8 articles about (4-Hydroxyphenyl)(pyrrolidin-1-yl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 4-(pyrrolidine-1-carbonyl)phenyl acetate

: 478929-28-1
(4-hydroxyphenyl)(pyrrolidin-1-yl)methanone

Guidance literature:: With sodium hydroxide; In methanol; water; at 20 ℃; for 1.33h;
DOI:10.1021/jm401115g

Reference yield: 80.0%

: 123-75-1
pyrrolidine

: 99-96-7
4-hydroxy-benzoic acid

: 478929-28-1
(4-hydroxyphenyl)(pyrrolidin-1-yl)methanone

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; Inert atmosphere;
DOI:10.1021/jacs.7b00049

Reference yield: 79.8%

: 123-75-1
pyrrolidine

: 27914-73-4
4-acetoxybenzoyl chloride

: 478929-28-1
(4-hydroxyphenyl)(pyrrolidin-1-yl)methanone

Guidance literature:: pyrrolidine; 4-acetoxybenzoyl chloride; In water; at 20 ℃; for 1h;

With sodium hydroxide; In water; for 1h;

With hydrogenchloride; In water; at 20 ℃; for 2h;
DOI:10.1016/j.ejmech.2008.04.018