(S)-2-Amino-3-(2,4,6-trifluorophenyl)propanoic acid

Base Information

Chemical Name:(S)-2-Amino-3-(2,4,6-trifluorophenyl)propanoic acid
CAS No.:481660-72-4
Molecular Formula:C9H8F3NO2
Molecular Weight:219.16100
Hs Code.:
DSSTox Substance ID:DTXSID50445740
Nikkaji Number:J1.410.329E
Mol file:481660-72-4.mol

Synonyms:(S)-2-Amino-3-(2,4,6-trifluorophenyl)propanoic acid;481660-72-4;(2S)-2-AMINO-3-(2,4,6-TRIFLUOROPHENYL)PROPANOIC ACID;2,4,6-trifluorophenylalanine;(S)-2-Amino-3-(2,4,6-trifluorophenyl)propanoicacid;SCHEMBL5672308;DTXSID50445740;2,4,6-Trifluoro-L-Phenylalanine;JS-4391

Suppliers and Price of (S)-2-Amino-3-(2,4,6-trifluorophenyl)propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(S)-2-Amino-3-(2,4,6-trifluorophenyl)propanoicacid 95+%
1g
$ 982.00

Chemenu
(S)-2-amino-3-(2,4,6-trifluorophenyl)propanoicacid 95%
1g
$ 926.00

American Custom Chemicals Corporation
2,4,6-TRIFLUORO-L-PHENYLALANINE 95.00%
5MG
$ 498.32

American Custom Chemicals Corporation
2,4,6-TRIFLUORO-L-PHENYLALANINE 95.00%
1G
$ 1204.35

Alichem
(S)-2-Amino-3-(2,4,6-trifluorophenyl)propanoicacid
1g
$ 1009.80

Total 9 raw suppliers

Chemical Property of (S)-2-Amino-3-(2,4,6-trifluorophenyl)propanoic acid

Chemical Property:

PSA：63.32000
LogP:1.75860
Storage Temp.:2-8°C
XLogP3:-1.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:219.05071298
Heavy Atom Count:15
Complexity:227

Purity/Quality:

99%, ^*data from raw suppliers

(S)-2-Amino-3-(2,4,6-trifluorophenyl)propanoicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C=C(C(=C1F)CC(C(=O)O)N)F)F
Isomeric SMILES:C1=C(C=C(C(=C1F)C[C@@H](C(=O)O)N)F)F

Technology Process of (S)-2-Amino-3-(2,4,6-trifluorophenyl)propanoic acid

There total 9 articles about (S)-2-Amino-3-(2,4,6-trifluorophenyl)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 151411-98-2
2-(bromomethyl)-1,3,5-trifluorobenzene

: 1259973-37-9,481660-72-4
L-2,4,6-trifluorophenylalanine

Guidance literature:: Multi-step reaction with 4 steps

1: Na; C₂H₅OH / 2 h / Heating

2: NaOH; HCl / methanol / 3 h / 40 °C

3: xylene / 2 h / 139 °C

4: NaOH; CH₃COONa; Aspergillus genus acylase / H₂O / 48 h / 38 °C

With hydrogenchloride; sodium hydroxide; ethanol; Aspergillus genus acylase; sodium acetate; sodium; In methanol; water; xylene;
DOI:10.1246/bcsj.73.2531

Reference yield:

: 151411-98-2
2-(bromomethyl)-1,3,5-trifluorobenzene

: 1259973-37-9,481660-72-4
(R)-2-Amino-3-(2,4,6-trifluoro-phenyl)-propionic acid

Guidance literature:: Multi-step reaction with 5 steps

1: Na; C₂H₅OH / 2 h / Heating

2: NaOH; HCl / methanol / 3 h / 40 °C

3: xylene / 2 h / 139 °C

4: NaOH; CH₃COONa; Aspergillus genus acylase / H₂O / 48 h / 38 °C

5: HCl / dioxane / 5 h / Heating

With hydrogenchloride; sodium hydroxide; ethanol; Aspergillus genus acylase; sodium acetate; sodium; In 1,4-dioxane; methanol; water; xylene;
DOI:10.1246/bcsj.73.2531

Reference yield:

: 324028-05-9
acetyl-DL-2,4,6-trifluorophenylalanine

: 1259973-37-9,481660-72-4
(R)-2-Amino-3-(2,4,6-trifluoro-phenyl)-propionic acid

Guidance literature:: Multi-step reaction with 2 steps

1: NaOH; CH₃COONa; Aspergillus genus acylase / H₂O / 48 h / 38 °C

2: HCl / dioxane / 5 h / Heating

With hydrogenchloride; sodium hydroxide; Aspergillus genus acylase; sodium acetate; In 1,4-dioxane; water;
DOI:10.1246/bcsj.73.2531