3-chloro-4-phenyl-1H-pyrrole-2,5-dione

Base Information

Chemical Name:3-chloro-4-phenyl-1H-pyrrole-2,5-dione
CAS No.:4840-61-3
Molecular Formula:C10H6ClNO2
Molecular Weight:207.616
Hs Code.:
Mol file:4840-61-3.mol

Synonyms:2-Chlor-α'-phenylmaleinsaeureimid;3-chloro-4-phenylpyrrole-2,5-dione;3-chloro- 4-phenylpyrrole-2,5-dione;3-chloro-4-phenyl-pyrrole-2,5-dione;

Suppliers and Price of 3-chloro-4-phenyl-1H-pyrrole-2,5-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 5 raw suppliers

Chemical Property of 3-chloro-4-phenyl-1H-pyrrole-2,5-dione

Chemical Property:

PSA：46.17000
LogP:1.62170

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-chloro-4-phenyl-1H-pyrrole-2,5-dione

There total 4 articles about 3-chloro-4-phenyl-1H-pyrrole-2,5-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 84863-93-4
3-hydroxy-4-phenyl-1H-pyrrole-2,5-dione

: 4840-61-3
3-chloro-4-phenyl-1H-pyrrole-2,5-dione

Guidance literature:: With oxalyl dichloride; In dichloromethane; N,N-dimethyl-formamide; at 20 ℃;
DOI:10.1002/ardp.200700190

Reference yield:

: 103-82-2
phenylacetic acid

: 4840-61-3
3-chloro-4-phenyl-1H-pyrrole-2,5-dione

Guidance literature:: Multi-step reaction with 4 steps

1: sulfuric acid / 12 h / Reflux

2: ammonium hydroxide / methanol / 15 h / 20 °C

3: potassium tert-butylate / tetrahydrofuran; N,N-dimethyl-formamide / 6 h / 0 - 20 °C

4: oxalyl dichloride / tetrahydrofuran; N,N-dimethyl-formamide / 4 h / 0 - 20 °C

With ammonium hydroxide; oxalyl dichloride; sulfuric acid; potassium tert-butylate; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.1039/c5nj02896e

Reference yield:

: 101-41-7
benzeneacetic acid methyl ester

: 4840-61-3
3-chloro-4-phenyl-1H-pyrrole-2,5-dione

Guidance literature:: Multi-step reaction with 3 steps

1: ammonium hydroxide / methanol / 15 h / 20 °C

2: potassium tert-butylate / tetrahydrofuran; N,N-dimethyl-formamide / 6 h / 0 - 20 °C

3: oxalyl dichloride / tetrahydrofuran; N,N-dimethyl-formamide / 4 h / 0 - 20 °C

With ammonium hydroxide; oxalyl dichloride; potassium tert-butylate; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.1039/c5nj02896e