(S)-2-Amino-3-(o-tolyl)propanoic acid

Base Information

Chemical Name:(S)-2-Amino-3-(o-tolyl)propanoic acid
CAS No.:22888-51-3
Molecular Formula:C10H13NO2
Molecular Weight:179.219
Hs Code.:2922499990
European Community (EC) Number:804-937-3
DSSTox Substance ID:DTXSID60945564
Nikkaji Number:J303.816E
Wikidata:Q72494625
ChEMBL ID:CHEMBL3808775
Mol file:22888-51-3.mol

Synonyms:80126-53-0;(S)-2-Amino-3-(o-tolyl)propanoic acid;L-2-Methylphenylalanine;H-PHE(2-ME)-OH;2-Methylphenylalanine;(2S)-2-amino-3-(2-methylphenyl)propanoic acid;D-2-Methylphenylalanine;L-2-METHYLPHE;L-2-ME-PHE-OH;2-METHY-L-PHENYLALANINE;Dl-2'-methylphenylalanine hydrochloride;Phenylalanine, 2-methyl-;(2S)-2-amino-3-(o-tolyl)propanoic acid;L-2-Methyl Phenylalanine;SCHEMBL43865;CHEMBL3808775;DTXSID60945564;NHBKDLSKDKUGSB-VIFPVBQESA-N;L-2-methylphenylalanine, AldrichCPR;MFCD00044971;AKOS012010208;AC-5866;CS-W017271;HY-W016555;PS-12169;(S)-2-AMINO-3-O-TOLYLPROPANOIC ACID;EN300-199907;L-2-Methylphenylalanine (H-L-Phe(2-Me)-OH);N10801;A839846;J-300416

Suppliers and Price of (S)-2-Amino-3-(o-tolyl)propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Dl-2''-MethylphenylalanineHydrochloride
500mg
$ 90.00

Crysdot
2-Amino-3-(o-tolyl)propanoicacid 97%
10g
$ 285.00

Chemenu
2-Amino-3-(o-tolyl)propanoicacid 97%
10g
$ 269.00

American Custom Chemicals Corporation
2-AMINO-3-O-TOLYL-PROPIONIC ACID 95.00%
25G
$ 1440.75

Ambeed
2-Amino-3-(o-tolyl)propanoicacid 97%
250mg
$ 22.00

Ambeed
2-Amino-3-(o-tolyl)propanoicacid 97%
10g
$ 324.00

Ambeed
2-Amino-3-(o-tolyl)propanoicacid 97%
1g
$ 54.00

Ambeed
2-Amino-3-(o-tolyl)propanoicacid 97%
5g
$ 183.00

AK Scientific
2-Amino-3-(o-tolyl)propanoicacid
5g
$ 165.00

AK Scientific
2-Amino-3-(o-tolyl)propanoicacid
1g
$ 45.00

Total 38 raw suppliers

Chemical Property of (S)-2-Amino-3-(o-tolyl)propanoic acid

Chemical Property:

Appearance/Colour:OFF-WHITE POWDER
Vapor Pressure:8.9E-05mmHg at 25°C
Melting Point:218.4-220.6 °C
Refractive Index:1.568
Boiling Point:326.211 °C at 760 mmHg
PKA:2.25±0.10(Predicted)
Flash Point:151.087 °C
PSA：63.32000
Density:1.166 g/cm³
LogP:2.45170
Storage Temp.:0-6°C
XLogP3:-1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:179.094628657
Heavy Atom Count:13
Complexity:182

Purity/Quality:

97% ^*data from raw suppliers

Dl-2''-MethylphenylalanineHydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=CC=C1CC(C(=O)O)N
Isomeric SMILES:CC1=CC=CC=C1C[C@@H](C(=O)O)N

Technology Process of (S)-2-Amino-3-(o-tolyl)propanoic acid

There total 8 articles about (S)-2-Amino-3-(o-tolyl)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 145243-36-3
2-(Benzhydrylidene-amino)-3-o-tolyl-propionic acid methyl ester

: 22888-51-3,1991-86-2,80126-54-1
2-amino-3-(2-methylphenyl)propanoic acid

Guidance literature:: With hydrogenchloride;
DOI:10.1021/jo00056a033

Reference yield:

: 5440-53-9
2-acetylamino-2-(2-methylbenzyl)malonic acid diethyl ester

: 22888-51-3,1991-86-2,80126-54-1
2-amino-3-(2-methylphenyl)propanoic acid

Guidance literature:: With hydrogen bromide;
DOI:10.1021/ja01572a065

Reference yield:

: 89-92-9
2-methylbenzyl bromide

: 22888-51-3,1991-86-2,80126-54-1
2-amino-3-(2-methylphenyl)propanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 72 percent / KOH, TEBAC

2: 76 percent / 6N HCl

With hydrogenchloride; potassium hydroxide; N-benzyl-N,N,N-triethylammonium chloride;
DOI:10.1021/jo00056a033