Carbamic acid, [(1R,3S,4R)-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-4-[[[(1,1-dimethyleth yl)dimethylsilyl]oxy]methyl]cyclopentyl]-, phenylmethyl ester

Base Information

Chemical Name:Carbamic acid, [(1R,3S,4R)-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-4-[[[(1,1-dimethyleth yl)dimethylsilyl]oxy]methyl]cyclopentyl]-, phenylmethyl ester
CAS No.:488151-70-8
Molecular Formula:C26H47NO4Si2
Molecular Weight:493.834
Hs Code.:

Carbamic acid,
[(1R,3S,4R)-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-4-[[[(1,1-dimethyleth
yl)dimethylsilyl]oxy]methyl]cyclopentyl]-, phenylmethyl ester

Synonyms:

Suppliers and Price of Carbamic acid, [(1R,3S,4R)-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-4-[[[(1,1-dimethyleth yl)dimethylsilyl]oxy]methyl]cyclopentyl]-, phenylmethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Carbamic acid, [(1R,3S,4R)-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-4-[[[(1,1-dimethyleth yl)dimethylsilyl]oxy]methyl]cyclopentyl]-, phenylmethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Carbamic acid, [(1R,3S,4R)-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-4-[[[(1,1-dimethyleth yl)dimethylsilyl]oxy]methyl]cyclopentyl]-, phenylmethyl ester

There total 8 articles about Carbamic acid, [(1R,3S,4R)-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-4-[[[(1,1-dimethyleth yl)dimethylsilyl]oxy]methyl]cyclopentyl]-, phenylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 100-51-6,185532-71-2
benzyl alcohol

: 1-(tert-butyl-dimethyl-silanyloxy)-2-(tert-butyl-dimethyl-silanyloxymethyl)-4-isocyanato-cyclopentane

: 488151-70-8
benzyl (1R,3S,4R)-N-[3-(t-butyldimethylsilyloxy)-4-((t-butyldimethylsilyl)oxy)methyl]cyclopentyl carbamate

: benzyl (1S,3S,4R)-N-[3-(t-butyldimethylsilyloxy)-4-((t-butyldimethylsilyl)oxy)methyl]cyclopentyl carbamate

Guidance literature:: With dibutyltin(II) dilaurate; In toluene; at 80 - 100 ℃; for 3.5h;
DOI:10.1246/bcsj.75.1771

Reference yield:

: 18162-48-6
tert-butyldimethylsilyl chloride

: 488151-70-8
benzyl (1R,3S,4R)-N-[3-(t-butyldimethylsilyloxy)-4-((t-butyldimethylsilyl)oxy)methyl]cyclopentyl carbamate

Guidance literature:: Multi-step reaction with 6 steps

1: 90 percent / imidazole / dimethylformamide / 10 h / 20 °C

2: 89 percent / dimethylsulfoxide; H₂O / 8 h / 170 °C

3: KOH / ethanol / 20 h / 30 °C

4: diphenoxyphosphoryl azide; (C₂H₅)3N / toluene / 1.5 h / 0 - 20 °C

5: toluene / 2 h / 80 °C

6: 201 mg / dibutyltin dilaurate / toluene / 3.5 h / 80 - 100 °C

With 1H-imidazole; dibutyltin(II) dilaurate; potassium hydroxide; diphenyl phosphoryl azide; water; dimethyl sulfoxide; triethylamine; In ethanol; N,N-dimethyl-formamide; toluene; 2: Krapcho dealkoxycarbonylation;
DOI:10.1246/bcsj.75.1771

Reference yield:

: 244277-08-5
dimethyl (3S,4R)-3-(t-butyldimethylsilyloxy)-4-[(t-butyldimethylsilyloxy)methyl]cyclopentane-1,1-dicarboxylate

: 488151-70-8
benzyl (1R,3S,4R)-N-[3-(t-butyldimethylsilyloxy)-4-((t-butyldimethylsilyl)oxy)methyl]cyclopentyl carbamate

Guidance literature:: Multi-step reaction with 5 steps

1: 89 percent / dimethylsulfoxide; H₂O / 8 h / 170 °C

2: KOH / ethanol / 20 h / 30 °C

3: diphenoxyphosphoryl azide; (C₂H₅)3N / toluene / 1.5 h / 0 - 20 °C

4: toluene / 2 h / 80 °C

5: 201 mg / dibutyltin dilaurate / toluene / 3.5 h / 80 - 100 °C

With dibutyltin(II) dilaurate; potassium hydroxide; diphenyl phosphoryl azide; water; dimethyl sulfoxide; triethylamine; In ethanol; toluene; 1: Krapcho dealkoxycarbonylation;
DOI:10.1246/bcsj.75.1771