5-Chloro-1,3-dimethyl-2,4,7-trioxo-8-phenylpyrido[2,3-d]pyrimidine-6-carbaldehyde

Base Information

Chemical Name:5-Chloro-1,3-dimethyl-2,4,7-trioxo-8-phenylpyrido[2,3-d]pyrimidine-6-carbaldehyde
CAS No.:177082-57-4
Molecular Formula:C16H12 Cl N3 O4
Molecular Weight:345.7372
Hs Code.:
DSSTox Substance ID:DTXSID20380715
Wikidata:Q82171140

Synonyms:5-chloro-1,3-dimethyl-2,4,7-trioxo-8-phenylpyrido[2,3-d]pyrimidine-6-carbaldehyde;177082-57-4;SCHEMBL2553725;DTXSID20380715

Suppliers and Price of 5-Chloro-1,3-dimethyl-2,4,7-trioxo-8-phenylpyrido[2,3-d]pyrimidine-6-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of 5-Chloro-1,3-dimethyl-2,4,7-trioxo-8-phenylpyrido[2,3-d]pyrimidine-6-carbaldehyde

Chemical Property:

Vapor Pressure:9.22E-07mmHg at 25°C
Boiling Point:404.8°Cat760mmHg
Flash Point:198.6°C
Density:1.56g/cm³
XLogP3:0.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:345.0516336
Heavy Atom Count:24
Complexity:706

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C2=C(C(=C(C(=O)N2C3=CC=CC=C3)C=O)Cl)C(=O)N(C1=O)C

Technology Process of 5-Chloro-1,3-dimethyl-2,4,7-trioxo-8-phenylpyrido[2,3-d]pyrimidine-6-carbaldehyde

There total 2 articles about 5-Chloro-1,3-dimethyl-2,4,7-trioxo-8-phenylpyrido[2,3-d]pyrimidine-6-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 137278-09-2
1,3-dimethyl-5-hydroxy-8-phenyl-1,2,3,4,7,8-hexahydropyrido<2,3-d>pyrimidine-2,4,7-trione

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 177082-57-4
5-chloro-6-formyl-1,3-dimethyl-8-phenyl-pyrido<2,3-d>pyrimidine-2,4,7(1H,3H,8H)-trione

Guidance literature:: With trichlorophosphate; at 50 - 60 ℃;
DOI:10.1002/prac.19963380129

Reference yield:

: 7278-51-5
6-anilino-1,3-dimethyluracil

: 177082-57-4
5-chloro-6-formyl-1,3-dimethyl-8-phenyl-pyrido<2,3-d>pyrimidine-2,4,7(1H,3H,8H)-trione

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / diphenyl ether / 2 h / 220 - 250 °C

2: 75 percent / POCl₃ / 50 - 60 °C

With trichlorophosphate; In diphenylether;
DOI:10.1002/prac.19963380129