2H-Pyrazolo(4,3-c)quinoline, 3,3a,4,5-tetrahydro-2-acetyl-8-methoxy-5-((4-methylphenyl)sulfonyl)-3-phenyl-, trans-

Base Information

Chemical Name:2H-Pyrazolo(4,3-c)quinoline, 3,3a,4,5-tetrahydro-2-acetyl-8-methoxy-5-((4-methylphenyl)sulfonyl)-3-phenyl-, trans-
CAS No.:78431-45-5
Molecular Formula:C₂₆H₂₅N₃O₄S
Molecular Weight:475.568
Hs Code.:
DSSTox Substance ID:DTXSID00229077
Wikidata:Q83109263

Synonyms:2H-Pyrazolo(4,3-c)quinoline, 3,3a,4,5-tetrahydro-2-acetyl-8-methoxy-5-((4-methylphenyl)sulfonyl)-3-phenyl-, trans-;78431-45-5;C26-H25-N3-O4-S;DTXSID00229077;LS-129344

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Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2H-Pyrazolo(4,3-c)quinoline, 3,3a,4,5-tetrahydro-2-acetyl-8-methoxy-5-((4-methylphenyl)sulfonyl)-3-phenyl-, trans-

Chemical Property:

Vapor Pressure:1.63E-17mmHg at 25°C
Boiling Point:664.3°C at 760 mmHg
Flash Point:355.5°C
Density:1.33g/cm³
XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:475.15657746
Heavy Atom Count:34
Complexity:886

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)N2CC3C(N(N=C3C4=C2C=CC(=C4)OC)C(=O)C)C5=CC=CC=C5
Isomeric SMILES:CC1=CC=C(C=C1)S(=O)(=O)N2C[C@@H]3[C@@H](N(N=C3C4=C2C=CC(=C4)OC)C(=O)C)C5=CC=CC=C5

Technology Process of 2H-Pyrazolo(4,3-c)quinoline, 3,3a,4,5-tetrahydro-2-acetyl-8-methoxy-5-((4-methylphenyl)sulfonyl)-3-phenyl-, trans-

There total 7 articles about 2H-Pyrazolo(4,3-c)quinoline, 3,3a,4,5-tetrahydro-2-acetyl-8-methoxy-5-((4-methylphenyl)sulfonyl)-3-phenyl-, trans- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 76263-68-8
6-Methoxy-3-[1-phenyl-meth-(E)-ylidene]-1-(toluene-4-sulfonyl)-2,3-dihydro-1H-quinolin-4-one

: 76263-73-5,78431-45-5
1-[(3S,3aR)-8-Methoxy-3-phenyl-5-(toluene-4-sulfonyl)-3,3a,4,5-tetrahydro-pyrazolo[4,3-c]quinolin-2-yl]-ethanone

Guidance literature:: With hydrazine hydrate; In acetic acid; for 8h; Heating;

Reference yield:

: 75227-41-7
N-tosyl-6-methoxy-2,3-dihydroquinolin-4-one

: 76263-73-5,78431-45-5
1-[(3S,3aR)-8-Methoxy-3-phenyl-5-(toluene-4-sulfonyl)-3,3a,4,5-tetrahydro-pyrazolo[4,3-c]quinolin-2-yl]-ethanone

Guidance literature:: Multi-step reaction with 2 steps

1: 91 percent / NaOCH₃ / methanol / 4 h / Ambient temperature

2: 97 percent / NH₂NH₂*H₂O / acetic acid / 8 h / Heating

With sodium methylate; hydrazine hydrate; In methanol; acetic acid;

Reference yield:

: 63767-58-8
ethyl 3?((4?methoxyphenyl)amino)propanoate

: 76263-73-5,78431-45-5
1-[(3S,3aR)-8-Methoxy-3-phenyl-5-(toluene-4-sulfonyl)-3,3a,4,5-tetrahydro-pyrazolo[4,3-c]quinolin-2-yl]-ethanone

Guidance literature:: Multi-step reaction with 6 steps

1: pyridine

2: KOH / methanol; H₂O / 16 h / Ambient temperature

3: PCl₅

4: SnCl₄

5: 91 percent / NaOCH₃ / methanol / 4 h / Ambient temperature

6: 97 percent / NH₂NH₂*H₂O / acetic acid / 8 h / Heating

With pyridine; potassium hydroxide; phosphorus pentachloride; sodium methylate; tin(IV) chloride; hydrazine hydrate; In methanol; water; acetic acid;