5-Bromo-4-iodopyridine-3-carboxylic acid

Base Information

Chemical Name:5-Bromo-4-iodopyridine-3-carboxylic acid
CAS No.:491588-98-8
Molecular Formula:C6H3BrINO2
Molecular Weight:327.904
Hs Code.:2933399990
European Community (EC) Number:663-121-3
DSSTox Substance ID:DTXSID20704457
Nikkaji Number:J1.773.685J
Wikidata:Q82636887
Mol file:491588-98-8.mol

Synonyms:491588-98-8;5-Bromo-4-iodonicotinic acid;5-Bromo-4-iodopyridine-3-carboxylic acid;5-Bromo-4-iodonicotinicacid;3-Pyridinecarboxylic acid, 5-bromo-4-iodo-;SCHEMBL16694995;DTXSID20704457;DDILUXVGWWORKX-UHFFFAOYSA-N;MFCD11656277;AKOS016012844;GS-6108;4-Iodo-5-bromopyridine-3-carboxylic acid;CS-0332011;FT-0745359;H10040;5-Bromo-4-iodopyridine-3-carboxylic acid, 96%

Suppliers and Price of 5-Bromo-4-iodopyridine-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
5-Bromo-4-iodopyridine-3-carboxylic acid 96%
1g
$ 104.00

Crysdot
5-Bromo-4-iodonicotinicacid 95+%
1g
$ 157.00

Crysdot
5-Bromo-4-iodonicotinicacid 95+%
5g
$ 501.00

Chemenu
5-bromo-4-iodonicotinicacid 95%
5g
$ 473.00

American Custom Chemicals Corporation
5-BROMO-4-IODOPYRIDINE-3-CARBOXYLIC ACID 95.00%
1G
$ 405.30

Ambeed
5-Bromo-4-iodonicotinicacid 95%
1g
$ 165.00

Ambeed
5-Bromo-4-iodonicotinicacid 95%
250mg
$ 54.00

Ambeed
5-Bromo-4-iodonicotinicacid 95%
100mg
$ 35.00

Alichem
5-Bromo-4-iodonicotinicacid
25g
$ 1667.00

Alichem
5-Bromo-4-iodonicotinicacid
10g
$ 970.00

Total 24 raw suppliers

Chemical Property of 5-Bromo-4-iodopyridine-3-carboxylic acid

Chemical Property:

Melting Point:158-163 °C (dec.)
PSA：50.19000
LogP:2.14690
Storage Temp.:2-8°C(protect from light)
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:326.83919
Heavy Atom Count:11
Complexity:167

Purity/Quality:

99%, ^*data from raw suppliers

5-Bromo-4-iodopyridine-3-carboxylic acid 96% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=C(C(=C(C=N1)Br)I)C(=O)O

Technology Process of 5-Bromo-4-iodopyridine-3-carboxylic acid

There total 1 articles about 5-Bromo-4-iodopyridine-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 20826-04-4
5-bromo-3-pyridinecarboxylic acid

: 491588-98-8
5-bromo-4-iodonicotinic acid

Guidance literature:: 5-bromo-3-pyridinecarboxylic acid; With 2,2,6,6-tetramethyl-piperidine; n-butyllithium; In tetrahydrofuran; hexane; at -50 ℃; for 0.5h;

With iodine; In tetrahydrofuran; hexane; at -50 ℃; for 2h;

With hydrogenchloride; In water; pH=3;
DOI:10.1016/S0040-4020(02)00673-7

Reference yield: 70.0%

: C₁₅H₂₂N₂O

: 491588-98-8
5-bromo-4-iodonicotinic acid

: C₂₁H₂₃BrIN₃O₂

Guidance literature:: With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In N,N-dimethyl-formamide; at 20 ℃; for 4h;

Reference yield: 62.0%

: 491588-98-8
5-bromo-4-iodonicotinic acid

: 49767-14-8
5-bromo-6-iodonicotinic acid

Guidance literature:: 5-bromo-4-iodonicotinic acid; With n-butyllithium; (tert-butyldimethylsilyl)-tert-butylamine; In tetrahydrofuran; hexane; at -50 ℃; for 30h;

With water; In tetrahydrofuran; hexane; at 20 ℃; for 0.5h;

With hydrogenchloride; In water; pH=3;
DOI:10.1016/S0040-4020(02)00673-7