3-Quinolinecarbonitrile,4-chloro-6-Methoxy-7-[3-(4-Methyl-1-piperazinyl)propoxy]-

Base Information

Chemical Name:3-Quinolinecarbonitrile,4-chloro-6-Methoxy-7-[3-(4-Methyl-1-piperazinyl)propoxy]-
CAS No.:492444-39-0
Molecular Formula:C19H23ClN4O2
Molecular Weight:374.87
Hs Code.:
Mol file:492444-39-0.mol

Synonyms:4-chloro-3-cyano-6-methoxy-7-[3-(4-methylpiperazine-1-yl)propoxy]quinoline;4-chloro-3-cyano-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline;

Suppliers and Price of 3-Quinolinecarbonitrile,4-chloro-6-Methoxy-7-[3-(4-Methyl-1-piperazinyl)propoxy]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Chloro-3-cyano-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline
100mg
$ 130.00

Crysdot
4-Chloro-6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinoline-3-carbonitrile 95+%
1g
$ 609.00

Chemenu
4-chloro-6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinoline-3-carbonitrile 95%
1g
$ 575.00

Total 15 raw suppliers

Chemical Property of 3-Quinolinecarbonitrile,4-chloro-6-Methoxy-7-[3-(4-Methyl-1-piperazinyl)propoxy]-

Chemical Property:

Melting Point:173 - 175oC
Boiling Point:548.7±50.0 °C(Predicted)
PKA:7.63±0.10(Predicted)
PSA：61.62000
Density:1.29±0.1 g/cm3(Predicted)
LogP:2.66058
Storage Temp.:Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility.:Acetonitrile (Slightly), Chloroform (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

4-Chloro-3-cyano-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 4-Chloro-3-cyano-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline is a useful reagent to prepare?benzofuranyl derivatives for treating solid tumours. It is also an impurity of Bosutinib.

Technology Process of 3-Quinolinecarbonitrile,4-chloro-6-Methoxy-7-[3-(4-Methyl-1-piperazinyl)propoxy]-

There total 10 articles about 3-Quinolinecarbonitrile,4-chloro-6-Methoxy-7-[3-(4-Methyl-1-piperazinyl)propoxy]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.5%

: C₁₉H₂₃ClN₄O₅

: 492444-39-0
7-[3-(4-methylpiperazin-1-yl)propoxy]-6-methoxy-4-chloro-quinoline-3-carbonitrile

Guidance literature:: With ammonium iodide; 5%-palladium/activated carbon; hydrogen; In methanol; at 30 - 35 ℃; for 7h; under 1500.15 - 2250.23 Torr; Reagent/catalyst; Solvent; Pressure; Temperature; Autoclave;