Benzoic acid, 2-hydroxy-5-(2-hydroxybenzoyl)-, ethyl ester

Base Information

• Chemical Name: Benzoic acid, 2-hydroxy-5-(2-hydroxybenzoyl)-, ethyl ester
• CAS No.: 494210-79-6
• Molecular Formula: C16H14O5
• Molecular Weight: 286.284
• DSSTox Substance ID: DTXSID70475706
• Nikkaji Number: J1.951.882E
• Wikidata: Q82306430
• Mol file: 494210-79-6.mol

Synonyms:494210-79-6;Benzoic acid, 2-hydroxy-5-(2-hydroxybenzoyl)-, ethyl ester;2-Hydroxy-5-(2-hydroxybenzoyl)benzoic acid ethyl ester;DTXSID70475706

Chemical Property of Benzoic acid, 2-hydroxy-5-(2-hydroxybenzoyl)-, ethyl ester

Chemical Property:

• XLogP3: 3.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 5
• Exact Mass: 286.08412354
• Heavy Atom Count: 21
• Complexity: 381

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)C1=C(C=CC(=C1)C(=O)C2=CC=CC=C2O)O

Technology Process of Benzoic acid, 2-hydroxy-5-(2-hydroxybenzoyl)-, ethyl ester

There total 3 articles about Benzoic acid, 2-hydroxy-5-(2-hydroxybenzoyl)-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

ethyl 3-oxo-4-(triphenylphosphoranylidene)butanoate (13148-05-5) + 3-Formylchromone (17422-74-1) → 2-hydroxy-5-(2-hydroxybenzoyl)benzoic acid ethyl ester (494210-79-6)

Guidance literature:

ethyl 3-oxo-4-(triphenylphosphoranylidene)butanoate; With sodium hydride; In tetrahydrofuran; at 0 ℃; for 0.5h;

3-Formylchromone; In tetrahydrofuran; for 24h; Heating;

DOI:10.1055/s-2003-37104

Reference yield: 51.0%

3-Formylchromone (17422-74-1) + 1-ethoxy-1,3-bis[(trimethylsilyl)oxy]buta-1,3-diene (89186-81-2) → 2-hydroxy-5-(2-hydroxybenzoyl)benzoic acid ethyl ester (494210-79-6)

Guidance literature:

With trimethylsilyl trifluoromethanesulfonate; In dichloromethane; at 0 - 20 ℃;

DOI:10.1016/j.tetlet.2003.09.008

Reference yield:

2-hydroxy-6-trimethylsilanyloxy-5-(2-trimethylsilanyloxy-benzoyl)-cyclohexa-1,4-dienecarboxylic acid ethyl ester → 2-hydroxy-5-(2-hydroxybenzoyl)benzoic acid ethyl ester (494210-79-6)

Guidance literature:

With hydrogenchloride; In dichloromethane;

DOI:10.1002/ejoc.200600082

upstream raw materials:

ethyl 3-oxo-4-(triphenylphosphoranylidene)butanoate

3-Formylchromone

1-ethoxy-1,3-bis[(trimethylsilyl)oxy]buta-1,3-diene

Downstream raw materials:

5-(2-hydroxybenzoyl)salicylic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 494210-79-6 Benzoic acid, 2-hydroxy-5-(2-hydroxybenzoyl)-, ethyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send