Ethyl 3-(4-methoxyphenyl)-5-methylisoxazole-4-carboxylate

Base Information

Chemical Name:Ethyl 3-(4-methoxyphenyl)-5-methylisoxazole-4-carboxylate
CAS No.:495417-31-7
Molecular Formula:C14H15NO4
Molecular Weight:261.277
Hs Code.:2934999090
DSSTox Substance ID:DTXSID40446928
Wikidata:Q82265677
Mol file:495417-31-7.mol

Synonyms:ethyl 3-(4-methoxyphenyl)-5-methylisoxazole-4-carboxylate;495417-31-7;Ethyl 3-(4-methoxyphenyl)-5-methyl-1,2-oxazole-4-carboxylate;MFCD09756448;4-Isoxazolecarboxylic acid, 3-(4-methoxyphenyl)-5-methyl-, ethyl ester;SCHEMBL2775071;DTXSID40446928;Ethyl3-(4-Methoxyphenyl)-5-methylisoxazole-4-carboxylate;HMS1625A14;VUA41731;AKOS001787488;AS-38320;SY028326;CS-0314763;FT-0734497;A871784;3-(4-Methoxyphenyl)-5-methylisoxazole-4-carboxylic acid ethyl ester

Suppliers and Price of Ethyl 3-(4-methoxyphenyl)-5-methylisoxazole-4-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
Ethyl 3-(4-methoxyphenyl)-5-methylisoxazole-4-carboxylate
1g
$ 315.00

Matrix Scientific
3-(4-Methoxyphenyl)-5-methylisoxazole-4-carboxylic acid ethyl ester 95%+
1g
$ 728.00

Crysdot
Ethyl 3-(4-methoxyphenyl)-5-methylisoxazole-4-carboxylate 95+%
5g
$ 669.00

American Custom Chemicals Corporation
Ethyl 3-(4-methoxyphenyl)-5-methylisoxazole-4-carboxylate 95.00%
5MG
$ 498.23

AK Scientific
Ethyl 3-(4-methoxyphenyl)-5-methylisoxazole-4-carboxylate
1g
$ 377.00

Advanced Chemicals Intermediatesced Chemicals Intermediates
3-(4-Methoxy-phenyl)-5-methyl-isoxazole-4-carboxylicacidethylester 95%+
5g
$ 1225.25

Acints
3-(4-Methoxy-phenyl)-5-methyl-isoxazole-4-carboxylicacidethylester 95%+
5g
$ 1225.25

Acints
3-(4-Methoxy-phenyl)-5-methyl-isoxazole-4-carboxylicacidethylester 95%+
1g
$ 355.25

Total 4 raw suppliers

Chemical Property of Ethyl 3-(4-methoxyphenyl)-5-methylisoxazole-4-carboxylate

Chemical Property:

Boiling Point:407.0±45.0 °C(Predicted)
PKA:-3.99±0.50(Predicted)
PSA：61.56000
Density:1.159±0.06 g/cm3(Predicted)
LogP:2.83530
XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:261.10010796
Heavy Atom Count:19
Complexity:302

Purity/Quality:

97% ^*data from raw suppliers

Ethyl 3-(4-methoxyphenyl)-5-methylisoxazole-4-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=C(ON=C1C2=CC=C(C=C2)OC)C

Technology Process of Ethyl 3-(4-methoxyphenyl)-5-methylisoxazole-4-carboxylate

There total 6 articles about Ethyl 3-(4-methoxyphenyl)-5-methylisoxazole-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 54716-02-8
ethyl (E)-3-(1-pyrrolidino)-2-butenoate

: 38435-51-7
N-hydroxy-4-methoxy-benzenecarboximidoyl chloride

: 495417-31-7
ethyl 3-(4-methoxyphenyl)-5-methylisoxazole-4-carboxylate

Guidance literature:: With triethylamine; In ethanol; at 20 ℃;
DOI:10.1021/jm020354w

Reference yield:

: 1007476-32-5
sodium ethyl acetylacetate enolate

: 38435-51-7
N-hydroxy-4-methoxy-benzenecarboximidoyl chloride

: 495417-31-7
ethyl 3-(4-methoxyphenyl)-5-methylisoxazole-4-carboxylate

Guidance literature:: With sodium hydroxide; In methanol; water; at 20 ℃; for 1h; pH=10;
DOI:10.22159/ijpps.2019v11i4.31933

Reference yield:

: 3717-21-3,3717-22-4,140461-28-5,140461-29-6,3235-04-9
p-methoxyl benzaldoxime

: 2723-42-4,54716-02-8,70526-06-6
ethyl 3-pyrrolidinobut-2-enoate

: 495417-31-7
ethyl 3-(4-methoxyphenyl)-5-methylisoxazole-4-carboxylate

Guidance literature:: p-methoxyl benzaldoxime; With pyridine; N-chloro-succinimide; In chloroform; Heating;

ethyl 3-pyrrolidinobut-2-enoate; With triethylamine; In chloroform;
DOI:10.1016/j.bmcl.2009.11.070