Ethyl 3-(pyrrolidin-1-yl)but-2-enoate

Base Information

Chemical Name:Ethyl 3-(pyrrolidin-1-yl)but-2-enoate
CAS No.:2723-42-4
Molecular Formula:C₁₀H₁₇NO₂
Molecular Weight:183.25
Hs Code.:
European Community (EC) Number:665-094-3
DSSTox Substance ID:DTXSID501289143
Mol file:2723-42-4.mol

Synonyms:ethyl 3-(pyrrolidin-1-yl)but-2-enoate;2723-42-4;MFCD00014097;Ethyl(E)-3-(1-pyrrolidino)crotonate;2-Butenoic acid, 3-(1-pyrrolidinyl)-, ethyl ester;2-Methyl-3-pyrrolizinopropenoic acid ethyl ester;ethyl-3-pyrrolidino-2-butenoate;DTXSID501289143;AKOS028111535;Ethyl 3-(1-pyrrolidinyl)-2-butenoate;FT-0625806;FT-0682229;D81896

Suppliers and Price of Ethyl 3-(pyrrolidin-1-yl)but-2-enoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Atlantic Research Chemicals
Ethyl3-(Pyrrolidin-1-yl)but-2-enoate 95%
10gm:
$ 388.80

Atlantic Research Chemicals
Ethyl3-(Pyrrolidin-1-yl)but-2-enoate 95%
5gm:
$ 211.37

Total 7 raw suppliers

Chemical Property of Ethyl 3-(pyrrolidin-1-yl)but-2-enoate

Chemical Property:

Melting Point:28-30℃
PSA：29.54000
LogP:1.48700
XLogP3:1.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:183.125928785
Heavy Atom Count:13
Complexity:205

Purity/Quality:

99% ^*data from raw suppliers

Ethyl3-(Pyrrolidin-1-yl)but-2-enoate 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C=C(C)N1CCCC1

Technology Process of Ethyl 3-(pyrrolidin-1-yl)but-2-enoate

There total 3 articles about Ethyl 3-(pyrrolidin-1-yl)but-2-enoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 123-75-1
pyrrolidine

: 141-97-9
ethyl acetoacetate

: 2723-42-4,54716-02-8,70526-06-6
ethyl 3-pyrrolidinobut-2-enoate

Guidance literature:: at 20 ℃; for 16h; Inert atmosphere; Schlenk technique;
DOI:10.1021/acs.orglett.7b03943

Reference yield:

: 123-75-1
pyrrolidine

: 4341-76-8
Ethyl 2-butynoate

: 2723-42-4,54716-02-8,70526-06-6
ethyl 3-pyrrolidinobut-2-enoate

Guidance literature:: With [((1,2-bis(diphenylphosphino)ethane))Ni]-(OTf)2; In tetrahydrofuran; at 100 ℃; for 4h; Reagent/catalyst; Schlenk technique; Inert atmosphere;
DOI:10.1039/c3dt52648h