4-chloro-5-methyl-2-nitro-aniline

Base Information

• Chemical Name: 4-chloro-5-methyl-2-nitro-aniline
• CAS No.: 7149-73-7
• Molecular Formula: C7H7ClN2O2
• Molecular Weight: 186.6
• Mol file: 7149-73-7.mol

Synonyms:4-chloro-5-methyl-2-nitro-aniline;4-Chlor-5-methyl-2-nitroanilin;6-Chlor-4-nitro-3-amino-toluol;

Chemical Property of 4-chloro-5-methyl-2-nitro-aniline

Chemical Property:

• Vapor Pressure: 0.000124mmHg at 25°C
• Melting Point: 120-121 °C
• Boiling Point: 334.9°C at 760 mmHg
• PKA: -0.75±0.25(Predicted)
• Flash Point: 156.3°C
• PSA: 71.84000
• Density: 1.415g/cm³
• LogP: 3.24320

Purity/Quality:

95% ^*data from raw suppliers

4-CHLORO-5-METHYL-2-NITROANILINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-chloro-5-methyl-2-nitro-aniline

There total 6 articles about 4-chloro-5-methyl-2-nitro-aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-chloro-4-nitrotoluene (121-86-8) → 4-chloro-5-methyl-2-nitro-aniline (7149-73-7)

Guidance literature:

Multi-step reaction with 2 steps

1: HNO₃+H₂SO₄ / 40 - 45 °C / dann bei 90grad

2: alcohol; ammonia

With ethanol; sulfuric acid; ammonia; nitric acid;

Reference yield:

2-chloro-4,5-dinitro-toluene (56136-79-9) → 4-chloro-5-methyl-2-nitro-aniline (7149-73-7) + 5-chloro-4-methyl-2-nitroaniline (7149-80-6)

Guidance literature:

With ethanol; ammonia;

Reference yield:

2-methylchlorobenzene (95-49-8) → 4-chloro-5-methyl-2-nitro-aniline (7149-73-7)

Guidance literature:

Multi-step reaction with 2 steps

1: HNO₃+H₂SO₄ / 8 - 10 °C / man trennt die Isomeren durch aufeinanderfolgende fraktionierte Krystallisation aus konz. Schwefelsaeure und Alkohol

2: alcohol; ammonia

With ethanol; sulfuric acid; ammonia; nitric acid;

upstream raw materials:

N-(4-chloro-3-methylphenyl)acetamide

2-chloro-4,5-dinitro-toluene

ammonia

2-chloro-4-nitrotoluene

Downstream raw materials:

(4-chloro-5-methyl-2-nitro-phenyl)-phenyl-amine

4-chloro-5-methylbenzene-1,2-diamine

2,5-dichloro-4-nitrotoluene

4-chloro-5-methyl-N¹-phenyl-o-phenylenediamine