Technology Process of Carbonochloridic acid, 4-[bis(2-chloroethyl)amino]-2-fluorophenyl ester
There total 6 articles about Carbonochloridic acid, 4-[bis(2-chloroethyl)amino]-2-fluorophenyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
triethylamine;
In
tetrahydrofuran; toluene;
at 0 - 20 ℃;
for 3h;
DOI:10.1039/b111549a
- Guidance literature:
-
Multi-step reaction with 6 steps
1: acetic acid; H2O / 72 h / 20 °C
2: 38 percent / KOH / ethanol / 2 h / Heating
3: pyridine / 0.25 h / Heating
4: 824 mg / LiCl; pyridine / 0.25 h / Heating
5: 100 percent / HCl; H2 / 10percent Pd/C / ethanol / 3 h
6: 47 percent / Et3N / toluene; tetrahydrofuran / 3 h / 0 - 20 °C
With
pyridine; hydrogenchloride; potassium hydroxide; hydrogen; triethylamine; lithium chloride;
10percent Pd/C;
In
tetrahydrofuran; ethanol; water; acetic acid; toluene;
DOI:10.1039/b111549a
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 38 percent / KOH / ethanol / 2 h / Heating
2: pyridine / 0.25 h / Heating
3: 824 mg / LiCl; pyridine / 0.25 h / Heating
4: 100 percent / HCl; H2 / 10percent Pd/C / ethanol / 3 h
5: 47 percent / Et3N / toluene; tetrahydrofuran / 3 h / 0 - 20 °C
With
pyridine; hydrogenchloride; potassium hydroxide; hydrogen; triethylamine; lithium chloride;
10percent Pd/C;
In
tetrahydrofuran; ethanol; toluene;
DOI:10.1039/b111549a
