N,N-dibenzyl-2-chloro-9-methyl-9H-purin-6-amine

Base Information

Chemical Name:N,N-dibenzyl-2-chloro-9-methyl-9H-purin-6-amine
CAS No.:496955-48-7
Molecular Formula:C20H18ClN5
Molecular Weight:363.849
Hs Code.:
DSSTox Substance ID:DTXSID601199167
Nikkaji Number:J2.865.829J
Mol file:496955-48-7.mol

Synonyms:N,N-dibenzyl-2-chloro-9-methyl-9H-purin-6-amine;496955-48-7;SCHEMBL380633;DTXSID601199167;AS-84075;N,N-dibenzyl-2-chloro-9-methylpurin-6-amine;E85678;2-Chloro-9-methyl-N,N-bis(phenylmethyl)-9H-purin-6-amine

Suppliers and Price of N,N-dibenzyl-2-chloro-9-methyl-9H-purin-6-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of N,N-dibenzyl-2-chloro-9-methyl-9H-purin-6-amine

Chemical Property:

XLogP3:4.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:363.1250733
Heavy Atom Count:26
Complexity:418

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN1C=NC2=C1N=C(N=C2N(CC3=CC=CC=C3)CC4=CC=CC=C4)Cl

Technology Process of N,N-dibenzyl-2-chloro-9-methyl-9H-purin-6-amine

There total 3 articles about N,N-dibenzyl-2-chloro-9-methyl-9H-purin-6-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 496955-47-6
dibenzyl-(2-chloro-9H-purin-6-yl)amine

: 74-88-4
methyl iodide

: 496955-48-7
dibenzyl-(2-chloro-9-methyl-9H-purin-6-yl)amine

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 12h;
DOI:10.1021/jm058018d

Reference yield:

: 5451-40-1
2,6 dichloropurine

: 496955-48-7
dibenzyl-(2-chloro-9-methyl-9H-purin-6-yl)amine

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / diisopropylethylamine / ethanol / 20 h / Heating

2: 78 percent / K₂CO₃ / dimethylformamide / 12 h / 20 °C

With potassium carbonate; N-ethyl-N,N-diisopropylamine; In ethanol; N,N-dimethyl-formamide;
DOI:10.1021/jm058018d

Reference yield:

: 103-49-1
dibenzylamine

: 496955-48-7
dibenzyl-(2-chloro-9-methyl-9H-purin-6-yl)amine

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / diisopropylethylamine / ethanol / 20 h / Heating

2: 78 percent / K₂CO₃ / dimethylformamide / 12 h / 20 °C

With potassium carbonate; N-ethyl-N,N-diisopropylamine; In ethanol; N,N-dimethyl-formamide;
DOI:10.1021/jm058018d