1-(2-bromophenyl)-5-(trifluoromethyl)-1H-pyrazole

Base Information

Chemical Name:1-(2-bromophenyl)-5-(trifluoromethyl)-1H-pyrazole
CAS No.:497833-00-8
Molecular Formula:C10H6BrF3N2
Molecular Weight:291.06700
Hs Code.:
DSSTox Substance ID:DTXSID00473851
Nikkaji Number:J1.803.144B
Wikidata:Q82303507
Mol file:497833-00-8.mol

Synonyms:1-(2-bromophenyl)-5-(trifluoromethyl)-1H-pyrazole;497833-00-8;DTXSID00473851;FVOSOMGRYQKZCF-UHFFFAOYSA-N;AKOS011582061

Suppliers and Price of 1-(2-bromophenyl)-5-(trifluoromethyl)-1H-pyrazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-(2-Bromophenyl)-5-(trifluoromethyl)-1H-pyrazole 95+%
5g
$ 746.00

Chemenu
1-(2-bromophenyl)-5-(trifluoromethyl)-1H-pyrazole 95%
5g
$ 704.00

Alichem
1-(2-Bromophenyl)-5-(trifluoromethyl)-1H-pyrazole
1g
$ 400.00

Total 6 raw suppliers

Chemical Property of 1-(2-bromophenyl)-5-(trifluoromethyl)-1H-pyrazole

Chemical Property:

PSA：17.82000
LogP:3.65360
Storage Temp.:2-8°C
XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:289.96665
Heavy Atom Count:16
Complexity:247

Purity/Quality:

97% ^*data from raw suppliers

1-(2-Bromophenyl)-5-(trifluoromethyl)-1H-pyrazole 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)N2C(=CC=N2)C(F)(F)F)Br

Technology Process of 1-(2-bromophenyl)-5-(trifluoromethyl)-1H-pyrazole

There total 1 articles about 1-(2-bromophenyl)-5-(trifluoromethyl)-1H-pyrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 59938-06-6,17129-06-5
4-ethoxy-1,1,1-trifluoro-3-butene-2-one

: 16732-66-4
2-bromophenylhydrazine

: 497833-00-8
1-(2-bromophenyl)-5-(trifluoromethyl)pyrazole

Guidance literature:: 4-ethoxy-1,1,1-trifluoro-3-butene-2-one; 2-bromophenylhydrazine; In ethanol; for 2h; Heating;

With hydrogenchloride; In dichloromethane; at 1 ℃; for 25h; Further stages.;
DOI:10.1002/1099-0690(200209)2002:17<2913::AID-EJOC2913>3.0.CO;2-D

Reference yield: 82.0%

: 124-38-9,18923-20-1
carbon dioxide

: 497833-00-8
1-(2-bromophenyl)-5-(trifluoromethyl)pyrazole

: 497833-09-7
2-(5-trifluoromethyl-1-pyrazolyl)benzoic acid

Guidance literature:: 1-(2-bromophenyl)-5-(trifluoromethyl)pyrazole; With tert.-butyl lithium; In diethyl ether; pentane; at -75 ℃; for 0.0833333h;

carbon dioxide; Further stages.;
DOI:10.1002/1099-0690(200209)2002:17<2913::AID-EJOC2913>3.0.CO;2-D

Reference yield: 24.0%

: 124-38-9,18923-20-1
carbon dioxide

: 497833-00-8
1-(2-bromophenyl)-5-(trifluoromethyl)pyrazole

: 1-(2-bromophenyl)-5-trifluoromethyl-4-pyrazolecarboxylic acid

Guidance literature:: 1-(2-bromophenyl)-5-(trifluoromethyl)pyrazole; With n-butyllithium; N,N,N',N'',N'''-pentamethyldiethylenetriamine; diisopropylamine; In tetrahydrofuran; hexane; at -75 ℃; for 0.0833333h;

carbon dioxide; Further stages.;
DOI:10.1002/1099-0690(200209)2002:17<2913::AID-EJOC2913>3.0.CO;2-D