16732-66-4

Basic information

• Product Name: 2-bromophenylhydrazine
• Synonyms: 1-(2-Bromophenyl)hydrazine
• CAS NO: 16732-66-4
• Molecular Formula: C₆H₇BrN₂
• Molecular Weight: 187.04
• EINECS: 240-797-4
• Mol File: 16732-66-4.mol
• Article Data: 9

Chemical Properties

• Melting Point: 46-48 °C
• Boiling Point: 275.7 °C at 760 mmHg
• Flash Point: 120.5 °C
• Appearance: /
• Density: 1.666 g/cm³
• Vapor Pressure: 0.00502mmHg at 25°C
• Refractive Index: 1.68
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 4.59±0.10(Predicted)
• CAS DataBase Reference: 2-bromophenylhydrazine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromophenylhydrazine(16732-66-4)
• EPA Substance Registry System: 2-bromophenylhydrazine(16732-66-4)

Safety Data

• Hazardous Substances Data: 16732-66-4(Hazardous Substances Data)

Usage

General Description

2-bromophenylhydrazine is a chemical compound with the molecular formula C6H7BrN2. It is a derivative of hydrazine, which is commonly used in organic synthesis and pharmaceuticals. 2-bromophenylhydrazine is commonly used in the preparation of organic compounds and is also used as a reagent in chemical reactions. It has been studied for its potential applications in various fields, including as a biomedical compound for the treatment of diseases. It is important to handle 2-bromophenylhydrazine with care, as it is considered to be toxic and possibly carcinogenic. Overall, 2-bromophenylhydrazine is a versatile compound with potential applications in multiple industries.

InChI:InChI=1/C6H7BrN2/c7-5-3-1-2-4-6(5)9-8/h1-4,9H,8H2

Upstream product

• 7647-01-0 hydrogenchloride 
• 95-46-5 2-methylphenyl bromide 
• 50709-33-6 2-bromophenylhydrazine hydrochloride 
• 615-36-1 2-bromoaniline 

Downstream Products

• 71856-54-7 5-amino-1-(2-bromo-phenyl)-1H-pyrazole-4-carbonitrile 
• 79006-01-2 1-(2-Bromo-phenylamino)-3-phenyl-1,3-dihydro-indol-2-one 
• 184474-82-6 2-bromophenylaminophthalimide 
• 497833-00-8 1-(2-bromophenyl)-5-(trifluoromethyl)pyrazole 
• 299162-73-5 1-(2-bromophenyl)-5-phenyl-1H-pyrazole 
• 1002092-27-4 C₁₇H₁₂BrN₃O 
• 1002092-31-0 4-{[2-(2-bromophenyl)hydrazino]methylene}-3,4-dihydro-1H-[1]benzazepine-2,5-dione 
• 404932-62-3 2-(2-bromophenyl)-6-(2-methoxyphenyl)-4-phenyl-4,5-dihydro-1,2,4-triazin-3-(2H)-one 
• 1176887-37-8 N-(2-bromophenyl)-N'-[1-(naphth-1-yl)-ethylidene]-hydrazine 
• 1176887-36-7 N-(2-bromophenyl)-N'-[1-(2-chlorophenyl)-ethylidene]-hydrazine 
• 1176887-34-5 N-(2-bromophenyl)-N'-[1-(4-fluorophenyl)-ethylidene]-hydrazine 
• 100715-98-8 N-(2-bromophenyl)-N'-[1-phenyl-ethylidene]-hydrazine 
• 1176887-38-9 N-(2-bromophenyl)-N'-[1-(2-methyl-1-phenyl)-propylidene]-hydrazine 
• 1219443-93-2 1-methylindole-3-carboxaldehyde (2-bromophenyl)hydrazone 

Relevant articles and documents

ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME

An organometallic compound represented by Formula 1: wherein, in Formula 1, groups and variables are the same as described in the specification.

2-bromophenylhydrazine oxalate preparation method

The invention relates to a 2-bromophenylhydrazine oxalate preparation method. The method comprises the steps of diazotization, reduction, purification and salt formation. In the diazotization and reduction steps, a reaction liquid is kept strongly acidic with concentrated hydrochloric acid, such that smooth and complete reactions are ensured. In the reduction step, zinc powder-concentrated hydrochloric acid is adopted as a reducing agent for replacing sodium thiosulfate, sodium bisulfite, stannous chloride-hydrochloric acid and the like, such that reduction performance is good, yield is high, and reaction time is shortened. Impurities such as zinc hydroxide produced in the reaction are easy to remove, such that product impurity amount is low, and product purity is high. In the salt formation step, acetone is used for leaching, such that product purity is improved, and product appearance is ensured. The preparation method has the advantages of stable and reliable process, easy operation, and high product purity (product content is no lower than 99.2% as a result of high-performance liquid chromatography). A product yield is no lower than 42%. The method can completely satisfy market demands on 2-bromophenylhydrazine oxalate.

Facile and convenient synthesis of aryl hydrazines via copper-catalyzed C-N cross-coupling of aryl halides and hydrazine hydrate

An efficient and convenient method for the synthesis of aryl hydrazines has been developed via copper-catalyzed cross-coupling of aryl bromides and hydrazine with a readily accessible ligand and water as a solvent. The multigram scale procedure is applicable to aryl bromides bearing both moderately electron-donating and electron-withdrawing substituents in the aromatic nucleus. No column chromatography is required to obtain aryl hydrazine hydrochlorides in good yields.