methyl (3R)-3-amino-4-phenylmethoxybutanoate

Base Information

Chemical Name:methyl (3R)-3-amino-4-phenylmethoxybutanoate
CAS No.:497847-07-1
Molecular Formula:C12H17NO3
Molecular Weight:223.272
Hs Code.:
DSSTox Substance ID:DTXSID20479592
Nikkaji Number:J2.196.109D
Wikidata:Q82313706

Synonyms:497847-07-1;CTK1D0447;DTXSID20479592;methyl (3R)-3-amino-4-(benzyloxy)butanoate;EN300-1722659

Suppliers and Price of methyl (3R)-3-amino-4-phenylmethoxybutanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of methyl (3R)-3-amino-4-phenylmethoxybutanoate

Chemical Property:

XLogP3:0.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:223.12084340
Heavy Atom Count:16
Complexity:202

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)CC(COCC1=CC=CC=C1)N
Isomeric SMILES:COC(=O)C[C@H](COCC1=CC=CC=C1)N

Technology Process of methyl (3R)-3-amino-4-phenylmethoxybutanoate

There total 3 articles about methyl (3R)-3-amino-4-phenylmethoxybutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 279256-97-2
(R)-4-benzyloxy-3-(o-nitrobenzenesulfonamido)butanoic acid methyl ester

: 497847-07-1
(R)-3-Amino-4-benzyloxy-butyric acid methyl ester

Guidance literature:: With potassium carbonate; thiophenol; In N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(02)00722-6

Reference yield:

: 261159-47-1
(4S)-4-(benzyloxymethyl)-oxetan-2-one

: 497847-07-1
(R)-3-Amino-4-benzyloxy-butyric acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 4 Amgstroem molecular sieves / dimethylsulfoxide / 5 h / 50 °C

2: 272 mg / ethyl acetate; diethyl ether

3: PhSH; K₂CO₃ / dimethylformamide

With 4 A molecular sieve; potassium carbonate; thiophenol; In diethyl ether; dimethyl sulfoxide; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(02)00722-6

Reference yield:

: (R)-4-Benzyloxy-3-(2-nitro-benzenesulfonylamino)-butyric acid

: 497847-07-1
(R)-3-Amino-4-benzyloxy-butyric acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 272 mg / ethyl acetate; diethyl ether

2: PhSH; K₂CO₃ / dimethylformamide

With potassium carbonate; thiophenol; In diethyl ether; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(02)00722-6