279256-97-2

Upstream product

• 185614-95-3 racemic 4-benzyloxymethyl-β-propiolactone 
• 60656-87-3 benzyloxyacetoaldehyde 
• 261159-47-1 (4S)-4-(benzyloxymethyl)-oxetan-2-one 
• 27444-80-0 o-Nitrobenzenesulfonamide monosodium salt 
• 186581-53-3 diazomethane 

Downstream Products

• 312710-48-8 methyl (R)-4-(benzyloxy)-3-{[(tert-butoxy)carbonyl]amino}butanoate 
• 497847-07-1 (R)-3-Amino-4-benzyloxy-butyric acid methyl ester 

Relevant academic research and scientific papers

Divergent reaction pathways in amine additions to β-lactone electrophiles. An application to β-peptide synthesis

β-Lactone electrophiles are subject to regioselective addition-elimination (AE) or SN2 ring opening with various nitrogen-based nucleophiles. Primary and secondary amines promote AE ring opening to deliver products that are the functional equiv