2,6-Bis(chloromethyl)pyridine hydrochloride

Base Information

• Chemical Name: 2,6-Bis(chloromethyl)pyridine hydrochloride
• CAS No.: 55422-79-2
• Molecular Formula: C7H8Cl3N
• Molecular Weight: 212.506
• Hs Code.: 2933399090
• European Community (EC) Number: 814-353-0
• DSSTox Substance ID: DTXSID20970771
• NSC Number: 244971
• Mol file: 55422-79-2.mol

Synonyms:55422-79-2;2,6-BIS(CHLOROMETHYL)PYRIDINE HYDROCHLORIDE;2,6-DichloroMethyl pyridine hydrochloride;2,6-bis(chloromethyl)pyridine;hydrochloride;2,6-bis-(chloromethyl)pyridine hydrochloride;2,6-Bis(chloromethyl)pyridine, HCl;Pyridine, 2,6-bis(chloromethyl)-, hydrochloride;SCHEMBL6588203;DTXSID20970771;MFCD00185582;NSC244971;AKOS022190422;NSC-244971;BS-17054;FT-0651668;D83093;2,6-BIS(CHLOROMETHYL)PYRIDINEHYDROCHLORIDE;A830636;2,6-Bis(chloromethyl)pyridine--hydrogen chloride (1/1)

Chemical Property of 2,6-Bis(chloromethyl)pyridine hydrochloride

Chemical Property:

• Vapor Pressure: 0.00197mmHg at 25°C
• Melting Point: 73-78ºC(lit.)
• Boiling Point: 286.8 °C at 760 mmHg
• Flash Point: 127.2 °C
• PSA: 12.89000
• Density: 1.275 g/cm3
• LogP: 3.36120
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 210.972232
• Heavy Atom Count: 11
• Complexity: 87.6

Purity/Quality:

99%, ^*data from raw suppliers

2,6-Bis(chloromethyl)pyridineHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=NC(=C1)CCl)CCl.Cl

Technology Process of 2,6-Bis(chloromethyl)pyridine hydrochloride

There total 4 articles about 2,6-Bis(chloromethyl)pyridine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

2.6-bis(hydroxymethyl)pyridine (1195-59-1) → 2,6-bis(chloromethyl)pyridine hydrochloric acid (55422-79-2)

Guidance literature:

With thionyl chloride; In methanol;

Reference yield:

(6-methoxy-pyridin-2-yl)-methanol (63071-12-5) → 2,6-bis(chloromethyl)pyridine hydrochloric acid (55422-79-2)

Guidance literature:

With thionyl chloride; In dichloromethane; at 20 ℃; for 16h;

DOI:10.1002/adsc.200404282

Reference yield:

2,6-dimethylpyridine (108-48-5) → 2,6-bis(chloromethyl)pyridine hydrochloric acid (55422-79-2)

Guidance literature:

Multi-step reaction with 4 steps

1: potassium permanganate; water / 0.58 h / 75 - 80 °C

2: sulfuric acid

3: sodium tetrahydroborate; aluminum (III) chloride / tetrahydrofuran; toluene / 0 - 5 °C

4: thionyl chloride / methanol

With aluminum (III) chloride; sodium tetrahydroborate; potassium permanganate; thionyl chloride; sulfuric acid; water; In tetrahydrofuran; methanol; toluene;

upstream raw materials:

(6-methoxy-pyridin-2-yl)-methanol

2.6-bis(hydroxymethyl)pyridine

2,6-dimethylpyridine

Pyridine-2,6-dicarboxylic acid

Downstream raw materials:

2,6-bis{[(pyrid-2-ylmethyl)(tosyl)amino]methyl}pyridine

2-{[6-(chloromethyl)pyridin-2-yl]methyl}isoindoline-1,3-dione

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 55422-79-2 2,6-bis(chloromethyl)pyridine

Send

Send

Metric Ton KG G Pound L ML

Send

Send