Carbamic acid, (5-amino-3-(4-aminophenyl)-1,2-dihydropyrido(3,4-b)pyra zin-7-yl)-, ethyl ester

Base Information

Chemical Name:Carbamic acid, (5-amino-3-(4-aminophenyl)-1,2-dihydropyrido(3,4-b)pyra zin-7-yl)-, ethyl ester
CAS No.:82586-02-5
Molecular Formula:C16H18N6O2
Molecular Weight:0
Hs Code.:
Mol file:82586-02-5.mol

Synonyms:Carbamic acid,(5-amino-3-(4-aminophenyl)-1,2-dihydropyrido(3,4-b)pyrazin-7-yl)-,ethyl ester;N-[5-Amino-3-(4-aminophenyl)(1,2-dihydropyridino[5,4-b]pyrazin-7-yl)]ethoxycarboxamide;Ethyl (5-amino-3-(4-aminophenyl)-1,2-dihydropyrido(3,4-b)pyrazin-7-yl)carbamate;

Suppliers and Price of Carbamic acid, (5-amino-3-(4-aminophenyl)-1,2-dihydropyrido(3,4-b)pyra zin-7-yl)-, ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Carbamic acid, (5-amino-3-(4-aminophenyl)-1,2-dihydropyrido(3,4-b)pyra zin-7-yl)-, ethyl ester

Chemical Property:

Vapor Pressure:1.76E-11mmHg at 25°C
Boiling Point:534°C at 760 mmHg
Flash Point:276.8°C
PSA：131.14000
Density:1.48g/cm³
LogP:3.11030

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Carbamic acid, (5-amino-3-(4-aminophenyl)-1,2-dihydropyrido(3,4-b)pyra zin-7-yl)-, ethyl ester

There total 3 articles about Carbamic acid, (5-amino-3-(4-aminophenyl)-1,2-dihydropyrido(3,4-b)pyra zin-7-yl)-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 17.0%

: 82585-83-9
{6-Amino-5-nitro-4-[2-(4-nitro-phenyl)-2-oxo-ethylamino]-pyridin-2-yl}-carbamic acid ethyl ester

: 82586-02-5
[5-Amino-3-(4-amino-phenyl)-1,2-dihydro-pyrido[3,4-b]pyrazin-7-yl]-carbamic acid ethyl ester

Guidance literature:: With hydrogen; nickel; In 1,4-dioxane; ethanol; for 6h; under 760 Torr; Heating;
DOI:10.1021/jm00351a008

Reference yield:

: 82585-70-4
{6-Amino-4-[2-[(Z)-hydroxyimino]-2-(4-nitro-phenyl)-ethylamino]-5-nitro-pyridin-2-yl}-carbamic acid ethyl ester

: 82586-02-5
[5-Amino-3-(4-amino-phenyl)-1,2-dihydro-pyrido[3,4-b]pyrazin-7-yl]-carbamic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 65 percent / 1N aq. HCl / dioxane / 24 h / 60 °C

2: 17 percent / H₂ / Raney nickel / ethanol; dioxane / 6 h / 760 Torr / Heating

With hydrogenchloride; hydrogen; nickel; In 1,4-dioxane; ethanol;
DOI:10.1021/jm00351a008

Reference yield:

: 82585-41-9
2-Amino-1-(4-nitro-phenyl)-ethanone oxime

: 82586-02-5
[5-Amino-3-(4-amino-phenyl)-1,2-dihydro-pyrido[3,4-b]pyrazin-7-yl]-carbamic acid ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 44 percent / Et₃N / ethanol / 2 h / 75 °C

2: 65 percent / 1N aq. HCl / dioxane / 24 h / 60 °C

3: 17 percent / H₂ / Raney nickel / ethanol; dioxane / 6 h / 760 Torr / Heating

With hydrogenchloride; hydrogen; triethylamine; nickel; In 1,4-dioxane; ethanol;
DOI:10.1021/jm00351a008