ethyl N-[6-amino-4-[[(2E)-2-hydroxyimino-2-(4-nitrophenyl)ethyl]amino]-5-nitro-2-pyridyl]carbamate

Base Information

Chemical Name:ethyl N-[6-amino-4-[[(2E)-2-hydroxyimino-2-(4-nitrophenyl)ethyl]amino]-5-nitro-2-pyridyl]carbamate
CAS No.:82585-70-4
Molecular Formula:C16H17N7O7
Molecular Weight:419.3489
Hs Code.:
NSC Number:332886
DSSTox Substance ID:DTXSID30421769

Synonyms:NSC332886;82585-70-4;SCHEMBL13327986;DTXSID30421769;NSC-332886;Carbamic acid,6-amino-5-nitro-4-[(2-(4'-nitrophenyl)-2- oxoethyl)amino]pyridin-2-yl,ethyl ester,oxime;ethyl N-[6-amino-4-[[(2E)-2-hydroxyimino-2-(4-nitrophenyl)ethyl]amino]-5-nitro-2-pyridyl]carbamate

Suppliers and Price of ethyl N-[6-amino-4-[[(2E)-2-hydroxyimino-2-(4-nitrophenyl)ethyl]amino]-5-nitro-2-pyridyl]carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of ethyl N-[6-amino-4-[[(2E)-2-hydroxyimino-2-(4-nitrophenyl)ethyl]amino]-5-nitro-2-pyridyl]carbamate

Chemical Property:

Vapor Pressure:2.71E-19mmHg at 25°C
Boiling Point:677.7°C at 760 mmHg
Flash Point:363.7°C
Density:1.61g/cm³
XLogP3:3.2
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:11
Rotatable Bond Count:7
Exact Mass:419.11894591
Heavy Atom Count:30
Complexity:643

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)NC1=NC(=C(C(=C1)NCC(=NO)C2=CC=C(C=C2)[N+](=O)[O-])[N+](=O)[O-])N
Isomeric SMILES:CCOC(=O)NC1=NC(=C(C(=C1)NC/C(=N/O)/C2=CC=C(C=C2)[N+](=O)[O-])[N+](=O)[O-])N

Technology Process of ethyl N-[6-amino-4-[[(2E)-2-hydroxyimino-2-(4-nitrophenyl)ethyl]amino]-5-nitro-2-pyridyl]carbamate

There total 1 articles about ethyl N-[6-amino-4-[[(2E)-2-hydroxyimino-2-(4-nitrophenyl)ethyl]amino]-5-nitro-2-pyridyl]carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

: 6506-86-1
ethyl (6-amino-4-chloro-5-nitropyridin-2-yl)carbamate

: 82585-41-9
2-Amino-1-(4-nitro-phenyl)-ethanone oxime

: 82585-70-4
{6-Amino-4-[2-[(Z)-hydroxyimino]-2-(4-nitro-phenyl)-ethylamino]-5-nitro-pyridin-2-yl}-carbamic acid ethyl ester

Guidance literature:: With triethylamine; In ethanol; at 75 ℃; for 2h;
DOI:10.1021/jm00351a008

Reference yield: 65.0%

: 82585-70-4
{6-Amino-4-[2-[(Z)-hydroxyimino]-2-(4-nitro-phenyl)-ethylamino]-5-nitro-pyridin-2-yl}-carbamic acid ethyl ester

: 82585-83-9
{6-Amino-5-nitro-4-[2-(4-nitro-phenyl)-2-oxo-ethylamino]-pyridin-2-yl}-carbamic acid ethyl ester

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; at 60 ℃; for 24h;
DOI:10.1021/jm00351a008

Reference yield:

: 82585-70-4
{6-Amino-4-[2-[(Z)-hydroxyimino]-2-(4-nitro-phenyl)-ethylamino]-5-nitro-pyridin-2-yl}-carbamic acid ethyl ester

: 82586-02-5
[5-Amino-3-(4-amino-phenyl)-1,2-dihydro-pyrido[3,4-b]pyrazin-7-yl]-carbamic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 65 percent / 1N aq. HCl / dioxane / 24 h / 60 °C

2: 17 percent / H₂ / Raney nickel / ethanol; dioxane / 6 h / 760 Torr / Heating

With hydrogenchloride; hydrogen; nickel; In 1,4-dioxane; ethanol;
DOI:10.1021/jm00351a008