4-Chloro-6-(4-methoxyphenyl)quinoline

Base Information

Chemical Name:4-Chloro-6-(4-methoxyphenyl)quinoline
CAS No.:500127-41-3
Molecular Formula:C16H12ClNO
Molecular Weight:269.73
Hs Code.:
DSSTox Substance ID:DTXSID80459537
Nikkaji Number:J1.808.993I
Wikidata:Q82283326
Mol file:500127-41-3.mol

Synonyms:4-chloro-6-(4-methoxyphenyl)quinoline;500127-41-3;Quinoline, 4-chloro-6-(4-methoxyphenyl)-;DTXSID80459537;6-(4-methoxyphenyl)-4-chloroquinoline

Suppliers and Price of 4-Chloro-6-(4-methoxyphenyl)quinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
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Total 0 raw suppliers

Chemical Property of 4-Chloro-6-(4-methoxyphenyl)quinoline

Chemical Property:

XLogP3:4.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:269.0607417
Heavy Atom Count:19
Complexity:291

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=CC3=C(C=CN=C3C=C2)Cl

Technology Process of 4-Chloro-6-(4-methoxyphenyl)quinoline

There total 3 articles about 4-Chloro-6-(4-methoxyphenyl)quinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 5720-07-0
4-methoxyphenylboronic acid

: 40107-07-1
4-chloro-6-iodo-quinoline

: 500127-41-3
4-chloro-6-(4-methoxyphenyl)quinoline

Guidance literature:: With potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; water; at 64 ℃; for 15h; Further Variations:; Catalysts; Reaction partners; Reagents; Solvents; temperatures, reaction times; Product distribution;
DOI:10.1016/S0040-4039(02)01516-2

Reference yield: 99.0%

: 65340-70-7
6-bromo-4-chloroquinoline

: 5720-07-0
4-methoxyphenylboronic acid

: 500127-41-3
4-chloro-6-(4-methoxyphenyl)quinoline

Guidance literature:: With potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; water; at 100 ℃; for 0.5h;
DOI:10.1007/s11172-005-0239-y

Reference yield: 35.0%

: 5720-07-0
4-methoxyphenylboronic acid

: 40107-07-1
4-chloro-6-iodo-quinoline

: 500127-41-3
4-chloro-6-(4-methoxyphenyl)quinoline

: 4,6-bis-(4-methoxy-phenyl)-quinoline

Guidance literature:: With potassium phosphate; bis(triphenylphosphine)nickel(II) chloride; In 1,4-dioxane; at 100 ℃; for 15h;
DOI:10.1023/B:RUJO.0000013144.15578.2d