2-Propenoic acid, 3-[6-[[(2R,3S)-3-(acetyloxy)-5-oxo-2-(phenylseleno)-1-pyrrolidinyl]methyl ]-1,3-benzodioxol-5-yl]-, phenylmethyl ester, (2E)-

Base Information

Chemical Name:2-Propenoic acid, 3-[6-[[(2R,3S)-3-(acetyloxy)-5-oxo-2-(phenylseleno)-1-pyrrolidinyl]methyl ]-1,3-benzodioxol-5-yl]-, phenylmethyl ester, (2E)-
CAS No.:500213-30-9
Molecular Formula:C30H27NO7Se
Molecular Weight:592.507
Hs Code.:

Synonyms:

Suppliers and Price of 2-Propenoic acid, 3-[6-[[(2R,3S)-3-(acetyloxy)-5-oxo-2-(phenylseleno)-1-pyrrolidinyl]methyl ]-1,3-benzodioxol-5-yl]-, phenylmethyl ester, (2E)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-Propenoic acid, 3-[6-[[(2R,3S)-3-(acetyloxy)-5-oxo-2-(phenylseleno)-1-pyrrolidinyl]methyl ]-1,3-benzodioxol-5-yl]-, phenylmethyl ester, (2E)-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-Propenoic acid, 3-[6-[[(2R,3S)-3-(acetyloxy)-5-oxo-2-(phenylseleno)-1-pyrrolidinyl]methyl ]-1,3-benzodioxol-5-yl]-, phenylmethyl ester, (2E)-

There total 5 articles about 2-Propenoic acid, 3-[6-[[(2R,3S)-3-(acetyloxy)-5-oxo-2-(phenylseleno)-1-pyrrolidinyl]methyl ]-1,3-benzodioxol-5-yl]-, phenylmethyl ester, (2E)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 2495-35-4,25036-21-9
benzylacrylate

: 500213-26-3
(4S,5R)-4-acetoxy-N-(2-iodo-4,5-methylenedioxybenzyl)-5-phenylselenyl-2-pyrrolidinone

: 500213-30-9
(4S,5R)-(E)-4-acetoxy-N-(2-benzyloxycarbonylethenyl-4,5-methylenedioxybenzyl)-5-phenylselenyl-2-pyrrolidinone

Guidance literature:: With palladium(III) acetate; triethylamine; triphenylphosphine; In various solvent(s); at 100 ℃; for 14h;
DOI:10.3987/COM-02-9610

Reference yield:

: 69048-76-6
6-iodo-1,3-benzodioxole-5-methanol

: 500213-30-9
(4S,5R)-(E)-4-acetoxy-N-(2-benzyloxycarbonylethenyl-4,5-methylenedioxybenzyl)-5-phenylselenyl-2-pyrrolidinone

Guidance literature:: Multi-step reaction with 4 steps

1.1: 88 percent / PPh₃; DEAD / tetrahydrofuran / 1 h / 20 °C

2.1: NaBH₄ / ethanol; tetrahydrofuran / 1.5 h / 0 °C

2.2: 67 percent / p-TsOH*H₂O / CH₂Cl₂ / 2 h / 20 °C

3.1: 93 percent / pyridine / 12 h / 20 °C

4.1: 72 percent / Pd(OAc)3; PPh₃; Et₃N / various solvent(s) / 14 h / 100 °C

With pyridine; sodium tetrahydroborate; palladium(III) acetate; triethylamine; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; ethanol; 4.1: Heck reaction;
DOI:10.3987/COM-02-9610

Reference yield:

: 244260-64-8
(3S)-3-acetoxy-N-(2-iodo-4,5-methylenedioxybenzyl)-2,5-pyrrolidinedione

: 500213-30-9
(4S,5R)-(E)-4-acetoxy-N-(2-benzyloxycarbonylethenyl-4,5-methylenedioxybenzyl)-5-phenylselenyl-2-pyrrolidinone

Guidance literature:: Multi-step reaction with 3 steps

1.1: NaBH₄ / ethanol; tetrahydrofuran / 1.5 h / 0 °C

1.2: 67 percent / p-TsOH*H₂O / CH₂Cl₂ / 2 h / 20 °C

2.1: 93 percent / pyridine / 12 h / 20 °C

3.1: 72 percent / Pd(OAc)3; PPh₃; Et₃N / various solvent(s) / 14 h / 100 °C

With pyridine; sodium tetrahydroborate; palladium(III) acetate; triethylamine; triphenylphosphine; In tetrahydrofuran; ethanol; 3.1: Heck reaction;
DOI:10.3987/COM-02-9610