3-Oxazolidinecarboxylic acid, 4-[(3S,6S)-6-[4-[[[(1S)-1-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]-2- methoxy-2-oxoethyl]amino]carbonyl]-5-methyl-2-oxazolyl]-3-(1-hydroxy-1 -methylethyl)-10,10-dimethyl-1,4-dioxo-9,9-diphenyl-8-oxa-2,5-diaza-9- silaundec-1-yl]-2,2-dimethyl-, phenylmethyl ester, (4S)-

Base Information

Chemical Name:3-Oxazolidinecarboxylic acid, 4-[(3S,6S)-6-[4-[[[(1S)-1-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]-2- methoxy-2-oxoethyl]amino]carbonyl]-5-methyl-2-oxazolyl]-3-(1-hydroxy-1 -methylethyl)-10,10-dimethyl-1,4-dioxo-9,9-diphenyl-8-oxa-2,5-diaza-9- silaundec-1-yl]-2,2-dimethyl-, phenylmethyl ester, (4S)-
CAS No.:500342-68-7
Molecular Formula:C₆₂H₇₇N₅O₁₂Si₂
Molecular Weight:1140.49
Hs Code.:

3-Oxazolidinecarboxylic acid,
4-[(3S,6S)-6-[4-[[[(1S)-1-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]-2-
methoxy-2-oxoethyl]amino]carbonyl]-5-methyl-2-oxazolyl]-3-(1-hydroxy-1
-methylethyl)-10,10-dimethyl-1,4-dioxo-9,9-diphenyl-8-oxa-2,5-diaza-9-
silaundec-1-yl]-2,2-dimethyl-, phenylmethyl ester, (4S)-

Synonyms:

Suppliers and Price of 3-Oxazolidinecarboxylic acid, 4-[(3S,6S)-6-[4-[[[(1S)-1-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]-2- methoxy-2-oxoethyl]amino]carbonyl]-5-methyl-2-oxazolyl]-3-(1-hydroxy-1 -methylethyl)-10,10-dimethyl-1,4-dioxo-9,9-diphenyl-8-oxa-2,5-diaza-9- silaundec-1-yl]-2,2-dimethyl-, phenylmethyl ester, (4S)-

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Chemical Property of 3-Oxazolidinecarboxylic acid, 4-[(3S,6S)-6-[4-[[[(1S)-1-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]-2- methoxy-2-oxoethyl]amino]carbonyl]-5-methyl-2-oxazolyl]-3-(1-hydroxy-1 -methylethyl)-10,10-dimethyl-1,4-dioxo-9,9-diphenyl-8-oxa-2,5-diaza-9- silaundec-1-yl]-2,2-dimethyl-, phenylmethyl ester, (4S)-

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of 3-Oxazolidinecarboxylic acid, 4-[(3S,6S)-6-[4-[[[(1S)-1-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]-2- methoxy-2-oxoethyl]amino]carbonyl]-5-methyl-2-oxazolyl]-3-(1-hydroxy-1 -methylethyl)-10,10-dimethyl-1,4-dioxo-9,9-diphenyl-8-oxa-2,5-diaza-9- silaundec-1-yl]-2,2-dimethyl-, phenylmethyl ester, (4S)-

There total 9 articles about 3-Oxazolidinecarboxylic acid, 4-[(3S,6S)-6-[4-[[[(1S)-1-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]-2- methoxy-2-oxoethyl]amino]carbonyl]-5-methyl-2-oxazolyl]-3-(1-hydroxy-1 -methylethyl)-10,10-dimethyl-1,4-dioxo-9,9-diphenyl-8-oxa-2,5-diaza-9- silaundec-1-yl]-2,2-dimethyl-, phenylmethyl ester, (4S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 58479-61-1
tert-butylchlorodiphenylsilane

: 500342-68-7
4-[1-(2-(tert-butyl-diphenyl-silanyloxy)-1-{4-[2-(tert-butyl-diphenyl-silanyloxy)-1-methoxycarbonyl-ethylcarbamoyl]-5-methyl-oxazol-2-yl}-ethylcarbamoyl)-2-hydroxy-2-methyl-propylcarbamoyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid benzyl ester

Guidance literature:: Multi-step reaction with 7 steps

1: imidazole / dimethylformamide

2: H₂ / Pd-C / methanol

3: BOP; EtN(iPr)2 / dimethylformamide

4: trifluoroacetic acid / CHCl₃

5: PivCl; Et₃N; MS 4 Angstroem / dimethylformamide

6: LiOH / methanol

7: BOP; NEt(iPr)2 / dimethylformamide

With 1H-imidazole; lithium hydroxide; MS 4 Angstroem; hydrogen; pivaloyl chloride; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; palladium on activated charcoal; In methanol; chloroform; N,N-dimethyl-formamide;
DOI:10.1246/cl.2002.1098

Reference yield:

: 334832-21-2
(S)-5,2',2'-Trimethyl-4',5'-dihydro-[2,4']bioxazolyl-4,3'-dicarboxylic acid 3'-benzyl ester 4-methyl ester

: 500342-68-7
4-[1-(2-(tert-butyl-diphenyl-silanyloxy)-1-{4-[2-(tert-butyl-diphenyl-silanyloxy)-1-methoxycarbonyl-ethylcarbamoyl]-5-methyl-oxazol-2-yl}-ethylcarbamoyl)-2-hydroxy-2-methyl-propylcarbamoyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid benzyl ester

Guidance literature:: Multi-step reaction with 8 steps

1: trifluoroacetic acid / CHCl₃

2: imidazole / dimethylformamide

3: H₂ / Pd-C / methanol

4: BOP; EtN(iPr)2 / dimethylformamide

5: trifluoroacetic acid / CHCl₃

6: PivCl; Et₃N; MS 4 Angstroem / dimethylformamide

7: LiOH / methanol

8: BOP; NEt(iPr)2 / dimethylformamide

With 1H-imidazole; lithium hydroxide; MS 4 Angstroem; hydrogen; pivaloyl chloride; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; palladium on activated charcoal; In methanol; chloroform; N,N-dimethyl-formamide;
DOI:10.1246/cl.2002.1098

Reference yield:

: 2-((S)-1-Benzyloxycarbonylamino-2-hydroxy-ethyl)-5-methyl-oxazole-4-carboxylic acid methyl ester

: 500342-68-7
4-[1-(2-(tert-butyl-diphenyl-silanyloxy)-1-{4-[2-(tert-butyl-diphenyl-silanyloxy)-1-methoxycarbonyl-ethylcarbamoyl]-5-methyl-oxazol-2-yl}-ethylcarbamoyl)-2-hydroxy-2-methyl-propylcarbamoyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid benzyl ester

Guidance literature:: Multi-step reaction with 7 steps

1: imidazole / dimethylformamide

2: H₂ / Pd-C / methanol

3: BOP; EtN(iPr)2 / dimethylformamide

4: trifluoroacetic acid / CHCl₃

5: PivCl; Et₃N; MS 4 Angstroem / dimethylformamide

6: LiOH / methanol

7: BOP; NEt(iPr)2 / dimethylformamide

With 1H-imidazole; lithium hydroxide; MS 4 Angstroem; hydrogen; pivaloyl chloride; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; palladium on activated charcoal; In methanol; chloroform; N,N-dimethyl-formamide;
DOI:10.1246/cl.2002.1098