334832-21-2Relevant articles and documents
Useful synthesis of the main dehydrohexapeptide segment of a macrocyclic antibiotic, berninamycin B
Yamada, Takahiro,Okumura, Kazuo,Yonezawa, Yasuchika,Shin, Chung-Gi
, p. 102 - 103 (2007/10/03)
The useful synthesis of tetradehydrohexapeptide segment 2, which is the main skeleton of a macrocyclic antibiotic, berninamycin B, was first achieved. The skeleton 2 is constructed, in turn, of 2-[(Z)-1-amino-1-propenyl]-5-methyl-oxazole-4-carboxylic acid, α-dehydroalanine (ΔAla), L-Val, 2-[1-amino-1-ethenyl]-5-methyloxazole-4-carboxylic acid residues, besides L-Thr and ΔAla at the N- and C-termini, respectively.